Vessel‐On‐A‐Chip Coupled Proteomics Reveal Pressure‐Overload‐Induced Vascular Remodeling

Vessel‐On‐A‐Chip Coupled Proteomics Reveal Pressure‐Overload‐Induced Vascular Remodeling

Abstract Hypertension, the leading cause of cardiovascular disease and premature mortality, is characterized by increased vessel stretch and alterations in vascular smooth muscle cells (VSMCs). In this study, a vessel‐on‐a‐chip model is developed to simulate both physiological and pathological stret...

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Bibliographic Details
Main Authors: Yanjun Liu, Jianxujie Zheng, Lingyan Zhong, Zengyu Wang, Dan Zhao, Hong Lin, Xiaoxue Zhang, Ke Meng, Xiaoxia Yang, Dongxue Zhang, Ling Lin, Liang Qiao
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
hypertension
microfluidics
proteomics
smooth muscle cells
vessel‐on‐a‐chip
Online Access:https://doi.org/10.1002/advs.202415024
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