A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies
Complex movement disorder is a relatively rare presentation of neurolupus. Antiphospholipid antibodies are associated with movement disorders likely via aberrant neuronal stimulation. Antiribosomal P antibodies have been previously associated with neuropsychiatric disorders but their correlation wit...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/590729 |
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| author | Muhammed Emin Özcan Meriç Adil Altınöz Hasan Hüseyin Karadeli Talip Asil Abdulkadir Koçer |
| author_facet | Muhammed Emin Özcan Meriç Adil Altınöz Hasan Hüseyin Karadeli Talip Asil Abdulkadir Koçer |
| author_sort | Muhammed Emin Özcan |
| collection | DOAJ |
| description | Complex movement disorder is a relatively rare presentation of neurolupus. Antiphospholipid antibodies are associated with movement disorders likely via aberrant neuronal stimulation. Antiribosomal P antibodies have been previously associated with neuropsychiatric disorders but their correlation with movement disorder was not previously established. Our case report involves a 17-year-old Caucasian female patient positive for only antiribosomal P antibody and lupus anticoagulant who presented with a sudden onset of complex movement disorder. After complete cessation of physical signs with olanzapine, anticardiolipin and anti-β2 glycoprotein I antibodies became positive which indicates a likely discordance between movement disorder and antiphospholipid antibodies. This also indicates a potential causal role of antiribosomal P antibodies in inducing movement disorder. |
| format | Article |
| id | doaj-art-d1b17a5e5d2c44d2a2803c71b11c7c7d |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-d1b17a5e5d2c44d2a2803c71b11c7c7d2025-02-03T06:00:06ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/590729590729A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P AntibodiesMuhammed Emin Özcan0Meriç Adil Altınöz1Hasan Hüseyin Karadeli2Talip Asil3Abdulkadir Koçer4Department of Neurology, Bezmialem Vakıf University, Adnan Menderes Bulvarı, Vatan Caddesi, 34093 Fatih İstanbul, İstanbul, TurkeyDepartment of Molecular Biology, Haliç University, Büyükdere Caddesi No. 101, 34394 Mecidiyeköy İstanbul, İstanbul, TurkeyDepartment of Neurology, Bezmialem Vakıf University, Adnan Menderes Bulvarı, Vatan Caddesi, 34093 Fatih İstanbul, İstanbul, TurkeyDepartment of Neurology, Bezmialem Vakıf University, Adnan Menderes Bulvarı, Vatan Caddesi, 34093 Fatih İstanbul, İstanbul, TurkeyDepartment of Neurology, Medeniyet University, Dr. Erkin Caddesi, 34730 Kadıköy İstanbul, İstanbul, TurkeyComplex movement disorder is a relatively rare presentation of neurolupus. Antiphospholipid antibodies are associated with movement disorders likely via aberrant neuronal stimulation. Antiribosomal P antibodies have been previously associated with neuropsychiatric disorders but their correlation with movement disorder was not previously established. Our case report involves a 17-year-old Caucasian female patient positive for only antiribosomal P antibody and lupus anticoagulant who presented with a sudden onset of complex movement disorder. After complete cessation of physical signs with olanzapine, anticardiolipin and anti-β2 glycoprotein I antibodies became positive which indicates a likely discordance between movement disorder and antiphospholipid antibodies. This also indicates a potential causal role of antiribosomal P antibodies in inducing movement disorder.http://dx.doi.org/10.1155/2013/590729 |
| spellingShingle | Muhammed Emin Özcan Meriç Adil Altınöz Hasan Hüseyin Karadeli Talip Asil Abdulkadir Koçer A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies Case Reports in Neurological Medicine |
| title | A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies |
| title_full | A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies |
| title_fullStr | A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies |
| title_full_unstemmed | A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies |
| title_short | A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies |
| title_sort | 17 year old female with systemic lupus presents with complex movement disorder possible relationship with antiribosomal p antibodies |
| url | http://dx.doi.org/10.1155/2013/590729 |
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