Salivary microbiota and IgA responses are different in pre-diabetic individuals compared to normoglycemic controls

Salivary microbiota and IgA responses are different in pre-diabetic individuals compared to normoglycemic controls

IntroductionIn recent years, changes in the oral microbiota of patients with type 2 diabetes mellitus (T2DM) have been increasingly recognized. The salivary microbiota may also be altered in pre-diabetes, which is the earliest stage of abnormal blood glucose regulation and a reversible stage precedi...

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Main Authors: Nahoko Kato-Kogoe, Kouji Tsuda, Asako Kudo, Shoichi Sakaguchi, Michi Omori, Eri Komori, Mayu Ohmichi, Wataru Hamada, Shota Nakamura, Takashi Nakano, Junko Tamaki, Takaaki Ueno
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
pre-diabetes
microbiota
saliva
immunoglobulin A
16S rRNA
IgA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1591285/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1591285/full

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