Multifaceted microbial enzyme nattokinase: a comprehensive review on therapeutics applications, production technologies and intellectual property landscape

Multifaceted microbial enzyme nattokinase: a comprehensive review on therapeutics applications, production technologies and intellectual property landscape

Cardiovascular diseases (CVDs) have risen drastically after the COVID era as post-COVID symptoms. “Nattokinase” (NK), the thrombolytic enzyme, is known for its substrate-specific thrombolytic, protease, and fibrinolytic activity to ameliorate CVDs. Primarily, NK was isolated from Bacillus subtilis n...

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Bibliographic Details
Main Authors: Tirth Chetankumar Bhatt, Viralkumar B. Mandaliya, Munir Ibrahim, Avani Bhimani, Asmita Detroja, Jaykumar Koradiya, Gaurav Sanghvi, Ashok Kumar Bishoyi
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Biotechnology
Subjects:
Clinical trials
Fermentation technology
Nattokinase
Patent landscape
Purification methods
Online Access:http://www.sciencedirect.com/science/article/pii/S2590262825000474
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