Clinical Trials of Probiotic Strains in Selected Disease Entities
Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. Although their mechanism of action is not clearly explained, it is known that they positively modulate the immune system, which leads to immunity potentiation. A number of studies prov...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | International Journal of Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2020/8854119 |
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| _version_ | 1832546974196301824 |
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| author | Ruth Dudek-Wicher Adam Junka Justyna Paleczny Marzenna Bartoszewicz |
| author_facet | Ruth Dudek-Wicher Adam Junka Justyna Paleczny Marzenna Bartoszewicz |
| author_sort | Ruth Dudek-Wicher |
| collection | DOAJ |
| description | Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. Although their mechanism of action is not clearly explained, it is known that they positively modulate the immune system, which leads to immunity potentiation. A number of studies prove that probiotics strengthen cognitive functions, reduce anxiety, and regulate the lipid metabolism in the human body. Probiotics used in humans are most often of the Lactobacillus and Bifidobacterium species. However, as more research is conducted, new species with beneficial, probiotic properties are being discovered. This paper provides a review of available information about the influence of probiotics on human health. It summarizes the current knowledge on the mechanism of action of probiotics as well as clinical trial results proving their efficacy in allergic, neurodegenerative, and cardiac diseases. This review also discusses the data concerning the safety of probiotics in clinical treatment. |
| format | Article |
| id | doaj-art-d196ffbe29d0442bbd38d387fcb6f91f |
| institution | Kabale University |
| issn | 1687-918X 1687-9198 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Microbiology |
| spelling | doaj-art-d196ffbe29d0442bbd38d387fcb6f91f2025-02-03T06:46:37ZengWileyInternational Journal of Microbiology1687-918X1687-91982020-01-01202010.1155/2020/88541198854119Clinical Trials of Probiotic Strains in Selected Disease EntitiesRuth Dudek-Wicher0Adam Junka1Justyna Paleczny2Marzenna Bartoszewicz3Department of Pharmaceutical Microbiology and Parasitology, Faculty of Pharmacy, Medical University of Silesian Piasts, Wrocław, PolandDepartment of Pharmaceutical Microbiology and Parasitology, Faculty of Pharmacy, Medical University of Silesian Piasts, Wrocław, PolandDepartment of Pharmaceutical Microbiology and Parasitology, Faculty of Pharmacy, Medical University of Silesian Piasts, Wrocław, PolandDepartment of Pharmaceutical Microbiology and Parasitology, Faculty of Pharmacy, Medical University of Silesian Piasts, Wrocław, PolandProbiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. Although their mechanism of action is not clearly explained, it is known that they positively modulate the immune system, which leads to immunity potentiation. A number of studies prove that probiotics strengthen cognitive functions, reduce anxiety, and regulate the lipid metabolism in the human body. Probiotics used in humans are most often of the Lactobacillus and Bifidobacterium species. However, as more research is conducted, new species with beneficial, probiotic properties are being discovered. This paper provides a review of available information about the influence of probiotics on human health. It summarizes the current knowledge on the mechanism of action of probiotics as well as clinical trial results proving their efficacy in allergic, neurodegenerative, and cardiac diseases. This review also discusses the data concerning the safety of probiotics in clinical treatment.http://dx.doi.org/10.1155/2020/8854119 |
| spellingShingle | Ruth Dudek-Wicher Adam Junka Justyna Paleczny Marzenna Bartoszewicz Clinical Trials of Probiotic Strains in Selected Disease Entities International Journal of Microbiology |
| title | Clinical Trials of Probiotic Strains in Selected Disease Entities |
| title_full | Clinical Trials of Probiotic Strains in Selected Disease Entities |
| title_fullStr | Clinical Trials of Probiotic Strains in Selected Disease Entities |
| title_full_unstemmed | Clinical Trials of Probiotic Strains in Selected Disease Entities |
| title_short | Clinical Trials of Probiotic Strains in Selected Disease Entities |
| title_sort | clinical trials of probiotic strains in selected disease entities |
| url | http://dx.doi.org/10.1155/2020/8854119 |
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