Biomarkers in Nonalcoholic Fatty Liver Disease

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a chronic liver condition characterized by insulin resistance, type 2 diabetes and fat accumulation in the liver that may cause hepatic inflammation and progressive scarring leading to nonalcoholic steatohepatitis (NASH) and irreversible liver...

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Main Authors: Manuela G Neuman, Lawrence B Cohen, Radu M Nanau
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2014/757929
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author Manuela G Neuman
Lawrence B Cohen
Radu M Nanau
author_facet Manuela G Neuman
Lawrence B Cohen
Radu M Nanau
author_sort Manuela G Neuman
collection DOAJ
description BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a chronic liver condition characterized by insulin resistance, type 2 diabetes and fat accumulation in the liver that may cause hepatic inflammation and progressive scarring leading to nonalcoholic steatohepatitis (NASH) and irreversible liver damage (cirrhosis). As a result, there has been increased recognition of the need to assess and closely monitor individuals for risk factors of components of NAFLD and NASH, as well as the severity of these conditions using biomarkers.
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series Canadian Journal of Gastroenterology and Hepatology
spelling doaj-art-d183752f1170439fab66b0ce1e7e5d1e2025-08-20T02:19:55ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972014-01-01281160761810.1155/2014/757929Biomarkers in Nonalcoholic Fatty Liver DiseaseManuela G Neuman0Lawrence B Cohen1Radu M Nanau2In Vitro Drug Safety and Biotechnology, Faculty of Medicine, University of Toronto, CanadaDivision of Gastroenterology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, CanadaIn Vitro Drug Safety and Biotechnology, Faculty of Medicine, University of Toronto, CanadaBACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a chronic liver condition characterized by insulin resistance, type 2 diabetes and fat accumulation in the liver that may cause hepatic inflammation and progressive scarring leading to nonalcoholic steatohepatitis (NASH) and irreversible liver damage (cirrhosis). As a result, there has been increased recognition of the need to assess and closely monitor individuals for risk factors of components of NAFLD and NASH, as well as the severity of these conditions using biomarkers.http://dx.doi.org/10.1155/2014/757929
spellingShingle Manuela G Neuman
Lawrence B Cohen
Radu M Nanau
Biomarkers in Nonalcoholic Fatty Liver Disease
Canadian Journal of Gastroenterology and Hepatology
title Biomarkers in Nonalcoholic Fatty Liver Disease
title_full Biomarkers in Nonalcoholic Fatty Liver Disease
title_fullStr Biomarkers in Nonalcoholic Fatty Liver Disease
title_full_unstemmed Biomarkers in Nonalcoholic Fatty Liver Disease
title_short Biomarkers in Nonalcoholic Fatty Liver Disease
title_sort biomarkers in nonalcoholic fatty liver disease
url http://dx.doi.org/10.1155/2014/757929
work_keys_str_mv AT manuelagneuman biomarkersinnonalcoholicfattyliverdisease
AT lawrencebcohen biomarkersinnonalcoholicfattyliverdisease
AT radumnanau biomarkersinnonalcoholicfattyliverdisease