Release of Copper / Magnesium Ions from Hydroxyapatite-Based Fiber Scaffolds Hasten Bone Healing and Regeneration
Releasing inorganic ions from Ca/P biomaterials could provide an alternative approach to using growth factors to improve bone healing. Two types of hydroxyapatite HA fiber scaffolds, copper-doped (CuHA) and magnesium-doped (MgHA), were fabricated by using the sol-gel method. Two types of scaffolds...
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| Language: | English |
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middle technical university
2024-09-01
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| Series: | Journal of Techniques |
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| Online Access: | https://journal.mtu.edu.iq/index.php/MTU/article/view/2567 |
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| author | Adil Elrayah Jie Weng Dongqin Xiao Azher S Barrak |
| author_facet | Adil Elrayah Jie Weng Dongqin Xiao Azher S Barrak |
| author_sort | Adil Elrayah |
| collection | DOAJ |
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Releasing inorganic ions from Ca/P biomaterials could provide an alternative approach to using growth factors to improve bone healing. Two types of hydroxyapatite HA fiber scaffolds, copper-doped (CuHA) and magnesium-doped (MgHA), were fabricated by using the sol-gel method. Two types of scaffolds were immersed in simulated body fluid SPF (i,e, Phosphate Buffered Saline PBS) for 30 days. The results after immersions indicated the amount of Cu and Mg ions released from scaffolds. A low amount of Mg and Cu ions could improve vascular endothelial growth factor (VEGF) and angiogenesis around bone, thus can hasten bone healing and regeneration.
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| format | Article |
| id | doaj-art-d181646e626b4188b2d25a9f13429f56 |
| institution | Kabale University |
| issn | 1818-653X 2708-8383 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | middle technical university |
| record_format | Article |
| series | Journal of Techniques |
| spelling | doaj-art-d181646e626b4188b2d25a9f13429f562025-01-19T10:56:29Zengmiddle technical universityJournal of Techniques1818-653X2708-83832024-09-016310.51173/jt.v6i3.2567Release of Copper / Magnesium Ions from Hydroxyapatite-Based Fiber Scaffolds Hasten Bone Healing and RegenerationAdil Elrayah0Jie Weng1Dongqin Xiao2Azher S Barrak3Medicine Collage, Karary University, Omdurman, 12304, SudanKey Laboratory of Advanced Technologies of Materials (MOE), School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, ChinaResearch Institute of Tissue Engineering and Stem Cells, Nanchong Central Hospital, The Second Clinical College of North Sichuan Medical College, Nanchong, Sichuan, 637000 ChinaOzone NDT Consulting LLC, Fort Worth, Texas, USA Releasing inorganic ions from Ca/P biomaterials could provide an alternative approach to using growth factors to improve bone healing. Two types of hydroxyapatite HA fiber scaffolds, copper-doped (CuHA) and magnesium-doped (MgHA), were fabricated by using the sol-gel method. Two types of scaffolds were immersed in simulated body fluid SPF (i,e, Phosphate Buffered Saline PBS) for 30 days. The results after immersions indicated the amount of Cu and Mg ions released from scaffolds. A low amount of Mg and Cu ions could improve vascular endothelial growth factor (VEGF) and angiogenesis around bone, thus can hasten bone healing and regeneration. https://journal.mtu.edu.iq/index.php/MTU/article/view/2567ScaffoldsHydroxyapatiteIonsCopperMagnesium |
| spellingShingle | Adil Elrayah Jie Weng Dongqin Xiao Azher S Barrak Release of Copper / Magnesium Ions from Hydroxyapatite-Based Fiber Scaffolds Hasten Bone Healing and Regeneration Journal of Techniques Scaffolds Hydroxyapatite Ions Copper Magnesium |
| title | Release of Copper / Magnesium Ions from Hydroxyapatite-Based Fiber Scaffolds Hasten Bone Healing and Regeneration |
| title_full | Release of Copper / Magnesium Ions from Hydroxyapatite-Based Fiber Scaffolds Hasten Bone Healing and Regeneration |
| title_fullStr | Release of Copper / Magnesium Ions from Hydroxyapatite-Based Fiber Scaffolds Hasten Bone Healing and Regeneration |
| title_full_unstemmed | Release of Copper / Magnesium Ions from Hydroxyapatite-Based Fiber Scaffolds Hasten Bone Healing and Regeneration |
| title_short | Release of Copper / Magnesium Ions from Hydroxyapatite-Based Fiber Scaffolds Hasten Bone Healing and Regeneration |
| title_sort | release of copper magnesium ions from hydroxyapatite based fiber scaffolds hasten bone healing and regeneration |
| topic | Scaffolds Hydroxyapatite Ions Copper Magnesium |
| url | https://journal.mtu.edu.iq/index.php/MTU/article/view/2567 |
| work_keys_str_mv | AT adilelrayah releaseofcoppermagnesiumionsfromhydroxyapatitebasedfiberscaffoldshastenbonehealingandregeneration AT jieweng releaseofcoppermagnesiumionsfromhydroxyapatitebasedfiberscaffoldshastenbonehealingandregeneration AT dongqinxiao releaseofcoppermagnesiumionsfromhydroxyapatitebasedfiberscaffoldshastenbonehealingandregeneration AT azhersbarrak releaseofcoppermagnesiumionsfromhydroxyapatitebasedfiberscaffoldshastenbonehealingandregeneration |