Synthesis of Novel S-Glucosides Containing 5-Methylisoxazole Substituted 1,2,4-Triazole
Nine new S-β-D-glucosides containing 4-aryl-5-(5-methylisoxazol-3-yl)-1,2,4-triazol-3-thiols have been synthesized by the direct glycosylation of 4-aryl-5-(5-methylisoxazol-3-yl)-1,2,4-triazol-3-thiols with 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide in ethanol in the presence of potassium hyd...
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Format: | Article |
Language: | English |
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Wiley
2013-01-01
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Series: | Journal of Chemistry |
Online Access: | http://dx.doi.org/10.1155/2013/568907 |
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author | Shujun Chao Yingling Wang |
author_facet | Shujun Chao Yingling Wang |
author_sort | Shujun Chao |
collection | DOAJ |
description | Nine new S-β-D-glucosides containing 4-aryl-5-(5-methylisoxazol-3-yl)-1,2,4-triazol-3-thiols have been synthesized by the direct glycosylation of 4-aryl-5-(5-methylisoxazol-3-yl)-1,2,4-triazol-3-thiols with 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide in ethanol in the presence of potassium hydroxide followed by deacetylation using dry ammonia in dry methanol. All the compounds synthesized have been characterized by their elemental analyses and spectral data. |
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institution | Kabale University |
issn | 2090-9063 2090-9071 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Journal of Chemistry |
spelling | doaj-art-d17c969845634ac9bf6e1b9dea2dc7892025-02-03T01:28:37ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/568907568907Synthesis of Novel S-Glucosides Containing 5-Methylisoxazole Substituted 1,2,4-TriazoleShujun Chao0Yingling Wang1Department of Chemistry, Xinxiang Medical University, Henan, Xinxiang 453003, ChinaDepartment of Chemistry, Xinxiang Medical University, Henan, Xinxiang 453003, ChinaNine new S-β-D-glucosides containing 4-aryl-5-(5-methylisoxazol-3-yl)-1,2,4-triazol-3-thiols have been synthesized by the direct glycosylation of 4-aryl-5-(5-methylisoxazol-3-yl)-1,2,4-triazol-3-thiols with 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide in ethanol in the presence of potassium hydroxide followed by deacetylation using dry ammonia in dry methanol. All the compounds synthesized have been characterized by their elemental analyses and spectral data.http://dx.doi.org/10.1155/2013/568907 |
spellingShingle | Shujun Chao Yingling Wang Synthesis of Novel S-Glucosides Containing 5-Methylisoxazole Substituted 1,2,4-Triazole Journal of Chemistry |
title | Synthesis of Novel S-Glucosides Containing 5-Methylisoxazole Substituted 1,2,4-Triazole |
title_full | Synthesis of Novel S-Glucosides Containing 5-Methylisoxazole Substituted 1,2,4-Triazole |
title_fullStr | Synthesis of Novel S-Glucosides Containing 5-Methylisoxazole Substituted 1,2,4-Triazole |
title_full_unstemmed | Synthesis of Novel S-Glucosides Containing 5-Methylisoxazole Substituted 1,2,4-Triazole |
title_short | Synthesis of Novel S-Glucosides Containing 5-Methylisoxazole Substituted 1,2,4-Triazole |
title_sort | synthesis of novel s glucosides containing 5 methylisoxazole substituted 1 2 4 triazole |
url | http://dx.doi.org/10.1155/2013/568907 |
work_keys_str_mv | AT shujunchao synthesisofnovelsglucosidescontaining5methylisoxazolesubstituted124triazole AT yinglingwang synthesisofnovelsglucosidescontaining5methylisoxazolesubstituted124triazole |