Distinctive features of blood- and ascitic fluid-derived extracellular vesicles in ovarian cancer patients

Distinctive features of blood- and ascitic fluid-derived extracellular vesicles in ovarian cancer patients

Abstract Background Ovarian cancer (OC) is a highly aggressive malignancy characterized by early dissemination of cancer cells from the surface of the ovary to the peritoneum. To gain a deeper understanding of the mechanisms associated with this intraperitoneal spread, we aimed to characterize the r...

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Main Authors: Francesca Gorini, Camelia Alexandra Coada, Sarah Monesmith, Antonio De Leo, Dario de Biase, Giulia Dondi, Stella Di Costanzo, Francesco Mezzapesa, Ivan Vannini, Mattia Melloni, Sara Bandini, Flora Guerra, Riccardo Di Corato, Pierandrea De Iaco, Patrizia Hrelia, Anna Myriam Perrone, Sabrina Angelini, Gloria Ravegnini
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Molecular Medicine
Subjects:
Ovarian cancer
Extracellular vesicles
Metastasis
Metastatic spread
miRNA
Online Access:https://doi.org/10.1186/s10020-025-01177-7
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