Effect of hemoglobin on non-traumatic rhabdomyolysis with acute renal failure

Objective To investigate the effect of hematoglobin level on rhabdomyolysis(RM)complicated with acute renal failure(ARF) and to identify its etiological factors,clinical features and outcome.Methods Data of 30 RM patients admitted in our hospital between July 1st 2011 and November 26 th 2014 was col...

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Bibliographic Details
Main Authors: LIU Sheng-cai, HE Li, MENG Xiang-yu, LIU Xiao-ping, LI Fei, LI Kai-li, LIU Shang-qin
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2016-01-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/thesisDetails?columnId=57919885&Fpath=home&index=0
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Summary:Objective To investigate the effect of hematoglobin level on rhabdomyolysis(RM)complicated with acute renal failure(ARF) and to identify its etiological factors,clinical features and outcome.Methods Data of 30 RM patients admitted in our hospital between July 1st 2011 and November 26 th 2014 was collected and retrospectively analyzed.We categorized these patients into two groups,one with co-existing ARF and one without Statistical analysis was performed for clinical data of these patients.Results Elevated creatine kinase(CK),myoglobin(Mb),lactate dehydrogenase(LDH),ALT,AST and serum creatinine(SCr) was found in all the patients.Hb,SCr and BUN were(89.8±22.7)g/L and(533.7±355.7)μmol/L and(0.0244±0.0146)mmol/L,in the 13 patients with ARF,and were(109.3±15.2)g/L,(209.4±159.5)μmol/L and(0.0179±0.0178)mmol/L in the 17 patients without ARF.The t-test for the difference in Hb level between the two groups indicated statistical significance(P=0.009),which was further confirmed by logistic regression.The difference in BUN and SCr between the two groups were both significant,with P=0.003 and 0.002 respectively.Conclusions Low Hb level could increase the risk of developing ARF in RM patients,which could be a risk factor for this situation.We conclude that monitoring Hb for patients diagnosed with RM is of large importance.
ISSN:1671-2390