Preclinical advance in nanoliposome-mediated photothermal therapy in liver cancer
Abstract Liver cancer is a highly lethal malignant tumor with a high incidence worldwide. Therefore, its treatment has long been a focus of medical research. Although traditional treatment methods such as surgery, radiotherapy, and chemotherapy have increased the survival rate of patients, their eff...
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| Format: | Article |
| Language: | English |
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BMC
2025-01-01
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| Series: | Lipids in Health and Disease |
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| Online Access: | https://doi.org/10.1186/s12944-024-02429-x |
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| author | Lixuan Tang Xiao Yang Liwen He Chaogeng Zhu Qingshan Chen |
| author_facet | Lixuan Tang Xiao Yang Liwen He Chaogeng Zhu Qingshan Chen |
| author_sort | Lixuan Tang |
| collection | DOAJ |
| description | Abstract Liver cancer is a highly lethal malignant tumor with a high incidence worldwide. Therefore, its treatment has long been a focus of medical research. Although traditional treatment methods such as surgery, radiotherapy, and chemotherapy have increased the survival rate of patients, their efficacy remains unsatisfactory owing to the nonspecific distribution of drugs, high toxicity, and drug resistance of tumor tissues. In recent years, the application of nanotechnology in the medical field has opened a new avenue for the treatment of liver cancer. Among these treatment methods, photothermal therapy (PTT) based on nanoliposomes has attracted wide attention owing to its unique targeting and high efficiency. This article reviews the latest preclinical research progress of nanoliposome-based PTT for liver cancer and its metastasis, discusses the preclinical challenges in this field, and proposes directions for improvement, with the aim of improving the effectiveness of liver cancer treatment. |
| format | Article |
| id | doaj-art-d136d7113f6d4c3a9ff04e9887507647 |
| institution | Kabale University |
| issn | 1476-511X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Lipids in Health and Disease |
| spelling | doaj-art-d136d7113f6d4c3a9ff04e98875076472025-02-02T12:40:42ZengBMCLipids in Health and Disease1476-511X2025-01-0124112210.1186/s12944-024-02429-xPreclinical advance in nanoliposome-mediated photothermal therapy in liver cancerLixuan Tang0Xiao Yang1Liwen He2Chaogeng Zhu3Qingshan Chen4School of Medicine, Hunan University of Chinese Medicine The department of oncology, The First Hospital of Hunan University of Chinese MedicineSchool of Medicine, Hunan University of Chinese Medicine The department of hepatobiliary pancreatic hernia surgery, The First Hospital of Hunan University of Chinese Medicine The department of hepatobiliary pancreatic hernia surgery, The First Hospital of Hunan University of Chinese MedicineAbstract Liver cancer is a highly lethal malignant tumor with a high incidence worldwide. Therefore, its treatment has long been a focus of medical research. Although traditional treatment methods such as surgery, radiotherapy, and chemotherapy have increased the survival rate of patients, their efficacy remains unsatisfactory owing to the nonspecific distribution of drugs, high toxicity, and drug resistance of tumor tissues. In recent years, the application of nanotechnology in the medical field has opened a new avenue for the treatment of liver cancer. Among these treatment methods, photothermal therapy (PTT) based on nanoliposomes has attracted wide attention owing to its unique targeting and high efficiency. This article reviews the latest preclinical research progress of nanoliposome-based PTT for liver cancer and its metastasis, discusses the preclinical challenges in this field, and proposes directions for improvement, with the aim of improving the effectiveness of liver cancer treatment.https://doi.org/10.1186/s12944-024-02429-xNanoliposomesPhotothermal therapyHepatocellular carcinomaSynergistic therapyProgressPhotothermal agent |
| spellingShingle | Lixuan Tang Xiao Yang Liwen He Chaogeng Zhu Qingshan Chen Preclinical advance in nanoliposome-mediated photothermal therapy in liver cancer Lipids in Health and Disease Nanoliposomes Photothermal therapy Hepatocellular carcinoma Synergistic therapy Progress Photothermal agent |
| title | Preclinical advance in nanoliposome-mediated photothermal therapy in liver cancer |
| title_full | Preclinical advance in nanoliposome-mediated photothermal therapy in liver cancer |
| title_fullStr | Preclinical advance in nanoliposome-mediated photothermal therapy in liver cancer |
| title_full_unstemmed | Preclinical advance in nanoliposome-mediated photothermal therapy in liver cancer |
| title_short | Preclinical advance in nanoliposome-mediated photothermal therapy in liver cancer |
| title_sort | preclinical advance in nanoliposome mediated photothermal therapy in liver cancer |
| topic | Nanoliposomes Photothermal therapy Hepatocellular carcinoma Synergistic therapy Progress Photothermal agent |
| url | https://doi.org/10.1186/s12944-024-02429-x |
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