Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency

In this study, we describe an fMRI version of the verbal fluency test. This is the second in a series of fMRI adaptations of classical neuropsychological tests, for which normative samples of functional activation have been collected from unimpaired control subjects and structured in a manner that m...

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Main Authors: Mark D. Allen, Alina K. Fong
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.3233/BEN-2008-0224
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author Mark D. Allen
Alina K. Fong
author_facet Mark D. Allen
Alina K. Fong
author_sort Mark D. Allen
collection DOAJ
description In this study, we describe an fMRI version of the verbal fluency test. This is the second in a series of fMRI adaptations of classical neuropsychological tests, for which normative samples of functional activation have been collected from unimpaired control subjects and structured in a manner that makes individual patient evaluation possible in terms of familiar z-score distributions. This fMRI protocol is shown to have strong convergent validity with the FAS phonemic fluency test and to elicit activation patterns highly consistent with a large body of previous neuroimaging studies of verbal fluency. We also present a case study, in which we report concurrent data from a patient with selective deficits in verbal processing, using both conventional neuropsychological and fMRI approaches. These analyses reveal striking correspondences between the deficits present in this patient on cognitive performance tests and the equally selective patterns of deviation present in his fMRI data.
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spelling doaj-art-d120102a8b624b20ae260f7094e0c22b2025-02-03T06:46:25ZengWileyBehavioural Neurology0953-41801875-85842008-01-01203-414115210.3233/BEN-2008-0224Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal FluencyMark D. Allen0Alina K. Fong1Psychology Department, Brigham Young University, Provo, UT, USAPsychology Department, Brigham Young University, Provo, UT, USAIn this study, we describe an fMRI version of the verbal fluency test. This is the second in a series of fMRI adaptations of classical neuropsychological tests, for which normative samples of functional activation have been collected from unimpaired control subjects and structured in a manner that makes individual patient evaluation possible in terms of familiar z-score distributions. This fMRI protocol is shown to have strong convergent validity with the FAS phonemic fluency test and to elicit activation patterns highly consistent with a large body of previous neuroimaging studies of verbal fluency. We also present a case study, in which we report concurrent data from a patient with selective deficits in verbal processing, using both conventional neuropsychological and fMRI approaches. These analyses reveal striking correspondences between the deficits present in this patient on cognitive performance tests and the equally selective patterns of deviation present in his fMRI data.http://dx.doi.org/10.3233/BEN-2008-0224
spellingShingle Mark D. Allen
Alina K. Fong
Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency
Behavioural Neurology
title Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency
title_full Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency
title_fullStr Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency
title_full_unstemmed Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency
title_short Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency
title_sort clinical application of standardized cognitive assessment using fmri ii verbal fluency
url http://dx.doi.org/10.3233/BEN-2008-0224
work_keys_str_mv AT markdallen clinicalapplicationofstandardizedcognitiveassessmentusingfmriiiverbalfluency
AT alinakfong clinicalapplicationofstandardizedcognitiveassessmentusingfmriiiverbalfluency