Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency
In this study, we describe an fMRI version of the verbal fluency test. This is the second in a series of fMRI adaptations of classical neuropsychological tests, for which normative samples of functional activation have been collected from unimpaired control subjects and structured in a manner that m...
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Format: | Article |
Language: | English |
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Wiley
2008-01-01
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Series: | Behavioural Neurology |
Online Access: | http://dx.doi.org/10.3233/BEN-2008-0224 |
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author | Mark D. Allen Alina K. Fong |
author_facet | Mark D. Allen Alina K. Fong |
author_sort | Mark D. Allen |
collection | DOAJ |
description | In this study, we describe an fMRI version of the verbal fluency test. This is the second in a series of fMRI adaptations of classical neuropsychological tests, for which normative samples of functional activation have been collected from unimpaired control subjects and structured in a manner that makes individual patient evaluation possible in terms of familiar z-score distributions. This fMRI protocol is shown to have strong convergent validity with the FAS phonemic fluency test and to elicit activation patterns highly consistent with a large body of previous neuroimaging studies of verbal fluency. We also present a case study, in which we report concurrent data from a patient with selective deficits in verbal processing, using both conventional neuropsychological and fMRI approaches. These analyses reveal striking correspondences between the deficits present in this patient on cognitive performance tests and the equally selective patterns of deviation present in his fMRI data. |
format | Article |
id | doaj-art-d120102a8b624b20ae260f7094e0c22b |
institution | Kabale University |
issn | 0953-4180 1875-8584 |
language | English |
publishDate | 2008-01-01 |
publisher | Wiley |
record_format | Article |
series | Behavioural Neurology |
spelling | doaj-art-d120102a8b624b20ae260f7094e0c22b2025-02-03T06:46:25ZengWileyBehavioural Neurology0953-41801875-85842008-01-01203-414115210.3233/BEN-2008-0224Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal FluencyMark D. Allen0Alina K. Fong1Psychology Department, Brigham Young University, Provo, UT, USAPsychology Department, Brigham Young University, Provo, UT, USAIn this study, we describe an fMRI version of the verbal fluency test. This is the second in a series of fMRI adaptations of classical neuropsychological tests, for which normative samples of functional activation have been collected from unimpaired control subjects and structured in a manner that makes individual patient evaluation possible in terms of familiar z-score distributions. This fMRI protocol is shown to have strong convergent validity with the FAS phonemic fluency test and to elicit activation patterns highly consistent with a large body of previous neuroimaging studies of verbal fluency. We also present a case study, in which we report concurrent data from a patient with selective deficits in verbal processing, using both conventional neuropsychological and fMRI approaches. These analyses reveal striking correspondences between the deficits present in this patient on cognitive performance tests and the equally selective patterns of deviation present in his fMRI data.http://dx.doi.org/10.3233/BEN-2008-0224 |
spellingShingle | Mark D. Allen Alina K. Fong Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency Behavioural Neurology |
title | Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency |
title_full | Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency |
title_fullStr | Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency |
title_full_unstemmed | Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency |
title_short | Clinical Application of Standardized Cognitive Assessment Using fMRI. II. Verbal Fluency |
title_sort | clinical application of standardized cognitive assessment using fmri ii verbal fluency |
url | http://dx.doi.org/10.3233/BEN-2008-0224 |
work_keys_str_mv | AT markdallen clinicalapplicationofstandardizedcognitiveassessmentusingfmriiiverbalfluency AT alinakfong clinicalapplicationofstandardizedcognitiveassessmentusingfmriiiverbalfluency |