Targeting Histone Deacetylase 11 with a Highly Selective Inhibitor for the Treatment of MASLD

Targeting Histone Deacetylase 11 with a Highly Selective Inhibitor for the Treatment of MASLD

Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) represents the most prevalent chronic liver disorder globally. Due to its intricate pathogenesis and the current lack of efficacious pharmacological interventions, there is a pressing need to discover novel therapeutic targets...

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Main Authors:	Feng Zhang, Kairui Yue, Simin Sun, Shengyuan Lu, Geng Jia, Yang Zha, Shuang Zhang, C. James Chou, Chenzhong Liao, Xiaoyang Li, Yajun Duan
Format:	Article
Language:	English
Published:	Wiley 2025-04-01
Series:	Advanced Science
Subjects:	AMP‐activated protein kinase de novo lipogenesis fatty acid oxidation histone deacetylase 11 metabolic dysfunction‐associated steatotic liver disease
Online Access:	https://doi.org/10.1002/advs.202412903
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