New Insights about Pulmonary Epithelioid Hemangioendothelioma: Review of the Literature and Two Case Reports

Pulmonary epithelioid hemangioendothelioma (PEH) is a rare neoplasm of vascular origin. There are three different major imaging patterns identified in thoracic manifestation of epithelioid hemangioendothelioma: (1) multiple pulmonary nodules; (2) multiple pulmonary reticulonodular opacities; and (3)...

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Main Authors: Romeu Duarte Mesquita, Marta Sousa, Carmen Trinidad, Eugénia Pinto, Iosu Antón Badiola
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2017/5972940
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author Romeu Duarte Mesquita
Marta Sousa
Carmen Trinidad
Eugénia Pinto
Iosu Antón Badiola
author_facet Romeu Duarte Mesquita
Marta Sousa
Carmen Trinidad
Eugénia Pinto
Iosu Antón Badiola
author_sort Romeu Duarte Mesquita
collection DOAJ
description Pulmonary epithelioid hemangioendothelioma (PEH) is a rare neoplasm of vascular origin. There are three different major imaging patterns identified in thoracic manifestation of epithelioid hemangioendothelioma: (1) multiple pulmonary nodules; (2) multiple pulmonary reticulonodular opacities; and (3) diffuse infiltrative pleural thickening. Radiographically, presence of bilateral multiple nodules is the most common pattern of presentation. The diagnosis is made on the basis of histopathological findings and confirmed by positive immunohistochemistry staining. Although the prognostic factors for PEH have not yet been well established, a better prognosis is usually associated with the multinodular pattern. We report two different imagological presentations of this rare disease, based on two institutional experiences, along with a review of the relevant literature.
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institution Kabale University
issn 2090-6862
2090-6870
language English
publishDate 2017-01-01
publisher Wiley
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series Case Reports in Radiology
spelling doaj-art-d102f6f862fb480e9920f6ce3216c8142025-02-03T05:46:23ZengWileyCase Reports in Radiology2090-68622090-68702017-01-01201710.1155/2017/59729405972940New Insights about Pulmonary Epithelioid Hemangioendothelioma: Review of the Literature and Two Case ReportsRomeu Duarte Mesquita0Marta Sousa1Carmen Trinidad2Eugénia Pinto3Iosu Antón Badiola4Department of Radiology, Centro Hospitalar de Entre o Douro e Vouga, Santa Maria da Feira, PortugalDepartment of Radiology, Centro Hospitalar de Entre o Douro e Vouga, Santa Maria da Feira, PortugalDepartment of Radiology, Hospital Povisa, Vigo, SpainDepartment of Pathology, Centro Hospitalar de Lisboa Central, Lisboa, PortugalDepartment of Pathology, Hospital Povisa, Vigo, SpainPulmonary epithelioid hemangioendothelioma (PEH) is a rare neoplasm of vascular origin. There are three different major imaging patterns identified in thoracic manifestation of epithelioid hemangioendothelioma: (1) multiple pulmonary nodules; (2) multiple pulmonary reticulonodular opacities; and (3) diffuse infiltrative pleural thickening. Radiographically, presence of bilateral multiple nodules is the most common pattern of presentation. The diagnosis is made on the basis of histopathological findings and confirmed by positive immunohistochemistry staining. Although the prognostic factors for PEH have not yet been well established, a better prognosis is usually associated with the multinodular pattern. We report two different imagological presentations of this rare disease, based on two institutional experiences, along with a review of the relevant literature.http://dx.doi.org/10.1155/2017/5972940
spellingShingle Romeu Duarte Mesquita
Marta Sousa
Carmen Trinidad
Eugénia Pinto
Iosu Antón Badiola
New Insights about Pulmonary Epithelioid Hemangioendothelioma: Review of the Literature and Two Case Reports
Case Reports in Radiology
title New Insights about Pulmonary Epithelioid Hemangioendothelioma: Review of the Literature and Two Case Reports
title_full New Insights about Pulmonary Epithelioid Hemangioendothelioma: Review of the Literature and Two Case Reports
title_fullStr New Insights about Pulmonary Epithelioid Hemangioendothelioma: Review of the Literature and Two Case Reports
title_full_unstemmed New Insights about Pulmonary Epithelioid Hemangioendothelioma: Review of the Literature and Two Case Reports
title_short New Insights about Pulmonary Epithelioid Hemangioendothelioma: Review of the Literature and Two Case Reports
title_sort new insights about pulmonary epithelioid hemangioendothelioma review of the literature and two case reports
url http://dx.doi.org/10.1155/2017/5972940
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