IL-1β primed mesenchymal stromal cells moderate hemorrhagic shock-induced vascular permeability

IL-1β primed mesenchymal stromal cells moderate hemorrhagic shock-induced vascular permeability

Abstract Background Hemorrhagic shock (HS) corresponds to absolute hypovolemia creating an imbalance between oxygen supply and consumption. This causes an impaired hemostasis, a systemic inflammatory response, and microvascular permeability which can lead to multiple organ failure (MOF). There is no...

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Bibliographic Details
Main Authors: Nathalie Baudry, Aurélie Campeanu, Clotilde Aussel, Caroline Doutrelon, Marion Grosbot, Sébastien Banzet, Eric Vicaut, Juliette Peltzer
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Translational Medicine
Subjects:
Mesenchymal stromal cells
Priming IL-1β
Hemorrhagic shock
Vascular permeability
Multiple organ failure
Online Access:https://doi.org/10.1186/s12967-024-05961-7
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