Toll-Like Receptors in Ischaemia and Its Potential Role in the Pathophysiology of Muscle Damage in Critical Limb Ischaemia

Toll-Like Receptors in Ischaemia and Its Potential Role in the Pathophysiology of Muscle Damage in Critical Limb Ischaemia

Toll-like receptors (TLRs) are key receptors of the innate immune system which are expressed on immune and nonimmune cells. They are activated by both pathogen-associated molecular patterns and endogenous ligands. Activation of TLRs culminates in the release of proinflammatory cytokines, chemokines,...

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Bibliographic Details
Main Authors: Hemanshu Patel, Sidney G. Shaw, Xu Shi-Wen, David Abraham, Daryll M. Baker, Janice C. S. Tsui
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2012/121237
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