Single-cell transcriptomic reveals the peritoneal microenvironmental change in long-term peritoneal dialysis patients with ultrafiltration failure

Single-cell transcriptomic reveals the peritoneal microenvironmental change in long-term peritoneal dialysis patients with ultrafiltration failure

Summary: The microenvironmental changes in peritoneal dialysis effluent (PDE) after long-term vintage (LV) of PD in patients with ultrafiltration failure (LV_UF) are unclear. Single-cell sequencing revealed that peritoneal neutrophils were elevated in LV_UF patients, while MRC1-macrophage subcluster...

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Bibliographic Details
Main Authors: Xiangwen Diao, Cuixia Zhan, Hongjian Ye, Haishan Wu, Chunyan Yi, Jianxiong Lin, Haiping Mao, Wei Chen, Xiao Yang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Body substance sample
Integrative aspects of cell biology
Microenvironment
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224026087
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