From Brain to Blood: Uncovering Potential Therapeutical Targets and Biomarkers for Huntington’s Disease Using an Integrative RNA-Seq Analytical Platform (BDASeq<sup>®</sup>)

From Brain to Blood: Uncovering Potential Therapeutical Targets and Biomarkers for Huntington’s Disease Using an Integrative RNA-Seq Analytical Platform (BDASeq<sup>®</sup>)

Background: Huntington’s Disease (HD) remains without disease-modifying treatments, with existing therapies primarily targeting chorea symptoms and offering limited benefits. This study aims to identify druggable genes and potential biomarkers for HD, focusing on using RNA-Seq analysis to uncover mo...

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Bibliographic Details
Main Authors: João Rafael Dias Pinto, Benedito Faustinoni Neto, Luciana Munhoz, Irina Kerkis, Rodrigo Pinheiro Araldi
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
Huntington’s disease
RNA-Seq
propensity score matching
druggable genes
FTH1
biomarker
Online Access:https://www.mdpi.com/2073-4409/14/13/976
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