Fertility Preservation in Girls

Children that undergo treatment for cancer are at risk of suffering from subfertility or hormonal dysfunction due to the detrimental effects of radiotherapy and chemotherapeutic agents on the gonads. Cryopreservation of ovarian tissue prior to treatment offers the possibility of restoring gonadal fu...

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Main Authors: Jennia Michaeli, Michael Weintraub, Eitan Gross, Yehuda Ginosar, Vardit Ravitsky, Einat Eizenman, Eduardo Mitrani, Meital Lebovich, Neri Laufer, Stephen Kennedy, Ariel Revel
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2012/139193
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author Jennia Michaeli
Michael Weintraub
Eitan Gross
Yehuda Ginosar
Vardit Ravitsky
Einat Eizenman
Eduardo Mitrani
Meital Lebovich
Neri Laufer
Stephen Kennedy
Ariel Revel
author_facet Jennia Michaeli
Michael Weintraub
Eitan Gross
Yehuda Ginosar
Vardit Ravitsky
Einat Eizenman
Eduardo Mitrani
Meital Lebovich
Neri Laufer
Stephen Kennedy
Ariel Revel
author_sort Jennia Michaeli
collection DOAJ
description Children that undergo treatment for cancer are at risk of suffering from subfertility or hormonal dysfunction due to the detrimental effects of radiotherapy and chemotherapeutic agents on the gonads. Cryopreservation of ovarian tissue prior to treatment offers the possibility of restoring gonadal function after resumption of therapy. Effective counseling and management of pediatric patients is crucial for preserving their future reproductive potential. The purpose of this article is to review recent literature and to revise recommendations we made in a 2007 article. Pediatric hemato-oncology, reproductive endocrinology, surgery, anesthesia and bioethics perspectives are discussed and integrated to propose guidelines for offering ovarian cryopreservation to premenarcheal girls with cancer.
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issn 1687-9589
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series Obstetrics and Gynecology International
spelling doaj-art-d0c0d42636f64e8eb29e8793a497cb0f2025-02-03T01:11:57ZengWileyObstetrics and Gynecology International1687-95891687-95972012-01-01201210.1155/2012/139193139193Fertility Preservation in GirlsJennia Michaeli0Michael Weintraub1Eitan Gross2Yehuda Ginosar3Vardit Ravitsky4Einat Eizenman5Eduardo Mitrani6Meital Lebovich7Neri Laufer8Stephen Kennedy9Ariel Revel10Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, 91120 Jerusalem, IsraelDepartment of Pediatric Hematology-Oncology, Hadassah-Hebrew University Medical Center, 91120 Jerusalem, IsraelDepartment of Pediatric Surgery, Hadassah-Hebrew University Medical Center, 91120 Jerusalem, IsraelDepartment of Anesthesiology, Hadassah-Hebrew University Medical Center, 91120 Jerusalem, IsraelBioethics Programs, Faculty of Medicine, University of Montreal, Montreal, QC, H3C 3J7, CanadaDepartment of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, 91120 Jerusalem, IsraelDepartment of Cell and Developmental Biology, Institute of Life Sciences, The Hebrew University of Jerusalem, 91904 Jerusalem, IsraelDepartment of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, 91120 Jerusalem, IsraelDepartment of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, 91120 Jerusalem, IsraelNuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, University of Oxford, Oxford QX1 2JD, UKDepartment of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, 91120 Jerusalem, IsraelChildren that undergo treatment for cancer are at risk of suffering from subfertility or hormonal dysfunction due to the detrimental effects of radiotherapy and chemotherapeutic agents on the gonads. Cryopreservation of ovarian tissue prior to treatment offers the possibility of restoring gonadal function after resumption of therapy. Effective counseling and management of pediatric patients is crucial for preserving their future reproductive potential. The purpose of this article is to review recent literature and to revise recommendations we made in a 2007 article. Pediatric hemato-oncology, reproductive endocrinology, surgery, anesthesia and bioethics perspectives are discussed and integrated to propose guidelines for offering ovarian cryopreservation to premenarcheal girls with cancer.http://dx.doi.org/10.1155/2012/139193
spellingShingle Jennia Michaeli
Michael Weintraub
Eitan Gross
Yehuda Ginosar
Vardit Ravitsky
Einat Eizenman
Eduardo Mitrani
Meital Lebovich
Neri Laufer
Stephen Kennedy
Ariel Revel
Fertility Preservation in Girls
Obstetrics and Gynecology International
title Fertility Preservation in Girls
title_full Fertility Preservation in Girls
title_fullStr Fertility Preservation in Girls
title_full_unstemmed Fertility Preservation in Girls
title_short Fertility Preservation in Girls
title_sort fertility preservation in girls
url http://dx.doi.org/10.1155/2012/139193
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