Molecular structures and in Silico molecular docking of new pyrazine-based heterocycles as antibacterial agents
Abstract Compound 2-(2-cyanoacetamido)pyrazine (3) serves as a key precursor for synthesizing various new pyrazine-linked heterocycles, including pyridine, thiazole, pyrazole, chromene, and pyrazolotriazine derivatives. Pyrazine-pyridone analogues 5a-d were obtained by reacting compound 3 with subst...
Saved in:
| Main Authors: | Mohamed R. Elmorsy, Sara H. Yousef, Ehab Abdel-Latif, Safa A. Badawy |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
|
| Series: | BMC Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13065-025-01535-w |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Design, synthesis, biological evaluation and molecular docking studies of novel pleuromutilin derivatives containing nitrogen heterocycle and alkylamine groups
by: Qi Wang, et al.
Published: (2022-12-01) -
Synthesis, molecular modeling and harnessing the antimicrobial activity of new pyrazine-thiadiazole hybrids
by: Hana M. Abumelha, et al.
Published: (2025-07-01) -
Synthesis, Characterization, Molecular Docking, and In Silico ADME Study for Some New Different Derivatives for Succiniohydrazide
by: Asmaa A. Maryoosh, et al.
Published: (2025-01-01) -
Molecular Docking Kaempferol sebagai Antiinflamasi pada Aterosklerosis secara In Silico
by: Gede Ngurah Hadi Candra, et al.
Published: (2021-03-01) -
Discovery and molecular characterization of a potent thiazolyl-pyrazole hybrid targeting EGFR for breast cancer therapy
by: Samar E. Mahmoud, et al.
Published: (2025-07-01)