Identification of novel cyclin-dependent kinase 4/6 inhibitors from marine natural products.

Identification of novel cyclin-dependent kinase 4/6 inhibitors from marine natural products.

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Cyclin-dependent kinases 4 and 6 (CDK4/6) are crucial regulators of cell cycle progression and represent important therapeutic targets in breast cancer. This study employs a comprehensive computational approach to identify novel CDK4/6 inhibitors from marine natural products. We utilized structure-b...

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Bibliographic Details
Main Authors: Abhijit Debnath, Rupa Mazumder, Anil Kumar Singh, Rajesh Kumar Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0313830
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