Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children
This paper provides an overview of insulin-induced hypoglycemia as a triggering factor of cognitive deficit in children with type 1 diabetes mellitus. For this purpose, databases from 1961 to 2013 were used with the objective of detecting the primary publications that address the impact of hypoglyce...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/616534 |
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| author | Vanessa Rodrigues Vilela Any de Castro Ruiz Marques Christiano Rodrigues Schamber Roberto Barbosa Bazotte |
| author_facet | Vanessa Rodrigues Vilela Any de Castro Ruiz Marques Christiano Rodrigues Schamber Roberto Barbosa Bazotte |
| author_sort | Vanessa Rodrigues Vilela |
| collection | DOAJ |
| description | This paper provides an overview of insulin-induced hypoglycemia as a triggering factor of cognitive deficit in children with type 1 diabetes mellitus. For this purpose, databases from 1961 to 2013 were used with the objective of detecting the primary publications that address the impact of hypoglycemia on cognitive performance of diabetic children. The results obtained from experimental animals were excluded. The majority of studies demonstrated that the cognitive deficit in diabetic children involves multiple factors including duration, intensity, severity, and frequency of hypoglycemia episodes. Additionally, age at the onset of type 1 diabetes also influences the cognitive performance, considering that early inception of the disease is a predisposing factor for severe hypoglycemia. Furthermore, the results suggest that there is a strong correlation between brain damage caused by hypoglycemia and cognitive deterioration. Therefore, a more cautious follow-up and education are needed to impede and treat hypoglycemia in children with diabetes mellitus. |
| format | Article |
| id | doaj-art-d0878037534c43ef9b92a4736cc94152 |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-d0878037534c43ef9b92a4736cc941522025-02-03T00:59:57ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/616534616534Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic ChildrenVanessa Rodrigues Vilela0Any de Castro Ruiz Marques1Christiano Rodrigues Schamber2Roberto Barbosa Bazotte3Department of Pharmacology and Therapeutics, State University of Maringá, 87020-900 Maringá, PR, BrazilDepartment of Pharmacology and Therapeutics, State University of Maringá, 87020-900 Maringá, PR, BrazilDepartment of Pharmacology and Therapeutics, State University of Maringá, 87020-900 Maringá, PR, BrazilDepartment of Pharmacology and Therapeutics, State University of Maringá, 87020-900 Maringá, PR, BrazilThis paper provides an overview of insulin-induced hypoglycemia as a triggering factor of cognitive deficit in children with type 1 diabetes mellitus. For this purpose, databases from 1961 to 2013 were used with the objective of detecting the primary publications that address the impact of hypoglycemia on cognitive performance of diabetic children. The results obtained from experimental animals were excluded. The majority of studies demonstrated that the cognitive deficit in diabetic children involves multiple factors including duration, intensity, severity, and frequency of hypoglycemia episodes. Additionally, age at the onset of type 1 diabetes also influences the cognitive performance, considering that early inception of the disease is a predisposing factor for severe hypoglycemia. Furthermore, the results suggest that there is a strong correlation between brain damage caused by hypoglycemia and cognitive deterioration. Therefore, a more cautious follow-up and education are needed to impede and treat hypoglycemia in children with diabetes mellitus.http://dx.doi.org/10.1155/2014/616534 |
| spellingShingle | Vanessa Rodrigues Vilela Any de Castro Ruiz Marques Christiano Rodrigues Schamber Roberto Barbosa Bazotte Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children The Scientific World Journal |
| title | Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children |
| title_full | Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children |
| title_fullStr | Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children |
| title_full_unstemmed | Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children |
| title_short | Hypoglycemia Induced by Insulin as a Triggering Factor of Cognitive Deficit in Diabetic Children |
| title_sort | hypoglycemia induced by insulin as a triggering factor of cognitive deficit in diabetic children |
| url | http://dx.doi.org/10.1155/2014/616534 |
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