Acceptance Factors and Psychological Investigation of Clinical Trials in Cancer Patients

Aim. To understand the degree of oncology patients’ awareness of drug clinical trials and oncology patients’ willingness to participate in drug clinical trials and the factors influencing them. Methods. The differences in the relevant variables of patients’ willingness to accept clinical trials were...

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Main Authors: Jiangjie Sun, Jingyi Fang, Chenchen Zhang, Nannan Jia, Weiming Zhao, Jinjian Gao, Yingying Huang, Jiqing Hao, Liping Zhang
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2023/5617575
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author Jiangjie Sun
Jingyi Fang
Chenchen Zhang
Nannan Jia
Weiming Zhao
Jinjian Gao
Yingying Huang
Jiqing Hao
Liping Zhang
author_facet Jiangjie Sun
Jingyi Fang
Chenchen Zhang
Nannan Jia
Weiming Zhao
Jinjian Gao
Yingying Huang
Jiqing Hao
Liping Zhang
author_sort Jiangjie Sun
collection DOAJ
description Aim. To understand the degree of oncology patients’ awareness of drug clinical trials and oncology patients’ willingness to participate in drug clinical trials and the factors influencing them. Methods. The differences in the relevant variables of patients’ willingness to accept clinical trials were analyzed, and a descriptive analysis was done for the measurement data (mean and standard deviation). Pearson’s correlation coefficient analysis was used to examine the correlation between willingness and the demographic variables. Stepwise regression analysis was used to explore the influencing factors of patients’ willingness to accept clinical trials. Results. There were no statistical differences in age, gender, education level, marital status, place of residence, monthly income, medical payment method, and treatment time (P>0.05). Patients’ willingness to accept drug clinical trials differed in their cognitive degree of clinical drug trials (P=0.002). Patients’ willingness to accept drug clinical trials differed in their experience in clinical trials (P<0.001). The correlation difference was statistically significant. The willingness to accept drug clinical trials was negatively correlated with treatment time (R=−0.16, P<0.05) and positively correlated with awareness of clinical trials and whether they had been subjects (R=0.16 and 0.43, P<0.05). Multiple regression analysis showed that patients’ willingness was directly influenced by age, treatment time, and whether they had been subjects (F=21.315, P<0.001). Conclusion. Age, treatment time, and whether they had been subjects were the direct influencing factors of patients’ willingness. This study pointed out that hospitals should do a good job in the publicity of clinical trials of new drugs, expand publicity channels, increase publicity efforts, improve the awareness of clinical trials of the masses, and promote the enthusiasm of the masses to participate in clinical trials of drugs.
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spelling doaj-art-d0869e2d207f4ad0bb6bdf24d6d05b242025-02-03T06:45:12ZengWileyBehavioural Neurology1875-85842023-01-01202310.1155/2023/5617575Acceptance Factors and Psychological Investigation of Clinical Trials in Cancer PatientsJiangjie Sun0Jingyi Fang1Chenchen Zhang2Nannan Jia3Weiming Zhao4Jinjian Gao5Yingying Huang6Jiqing Hao7Liping Zhang8School of ManagementFirst Clinical Medical CollegeFirst Affiliated Hospital of Anhui Medical UniversityFirst Clinical Medical CollegeFirst Clinical Medical CollegeFirst Clinical Medical CollegeFirst Clinical Medical CollegeFirst Affiliated Hospital of Anhui Medical UniversitySchool of MarxismAim. To understand the degree of oncology patients’ awareness of drug clinical trials and oncology patients’ willingness to participate in drug clinical trials and the factors influencing them. Methods. The differences in the relevant variables of patients’ willingness to accept clinical trials were analyzed, and a descriptive analysis was done for the measurement data (mean and standard deviation). Pearson’s correlation coefficient analysis was used to examine the correlation between willingness and the demographic variables. Stepwise regression analysis was used to explore the influencing factors of patients’ willingness to accept clinical trials. Results. There were no statistical differences in age, gender, education level, marital status, place of residence, monthly income, medical payment method, and treatment time (P>0.05). Patients’ willingness to accept drug clinical trials differed in their cognitive degree of clinical drug trials (P=0.002). Patients’ willingness to accept drug clinical trials differed in their experience in clinical trials (P<0.001). The correlation difference was statistically significant. The willingness to accept drug clinical trials was negatively correlated with treatment time (R=−0.16, P<0.05) and positively correlated with awareness of clinical trials and whether they had been subjects (R=0.16 and 0.43, P<0.05). Multiple regression analysis showed that patients’ willingness was directly influenced by age, treatment time, and whether they had been subjects (F=21.315, P<0.001). Conclusion. Age, treatment time, and whether they had been subjects were the direct influencing factors of patients’ willingness. This study pointed out that hospitals should do a good job in the publicity of clinical trials of new drugs, expand publicity channels, increase publicity efforts, improve the awareness of clinical trials of the masses, and promote the enthusiasm of the masses to participate in clinical trials of drugs.http://dx.doi.org/10.1155/2023/5617575
spellingShingle Jiangjie Sun
Jingyi Fang
Chenchen Zhang
Nannan Jia
Weiming Zhao
Jinjian Gao
Yingying Huang
Jiqing Hao
Liping Zhang
Acceptance Factors and Psychological Investigation of Clinical Trials in Cancer Patients
Behavioural Neurology
title Acceptance Factors and Psychological Investigation of Clinical Trials in Cancer Patients
title_full Acceptance Factors and Psychological Investigation of Clinical Trials in Cancer Patients
title_fullStr Acceptance Factors and Psychological Investigation of Clinical Trials in Cancer Patients
title_full_unstemmed Acceptance Factors and Psychological Investigation of Clinical Trials in Cancer Patients
title_short Acceptance Factors and Psychological Investigation of Clinical Trials in Cancer Patients
title_sort acceptance factors and psychological investigation of clinical trials in cancer patients
url http://dx.doi.org/10.1155/2023/5617575
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