Comparison of sepsis-associated acute kidney injury with different degrees and causes reveals patterns in mitochondrial metabolism and immune infiltration changes

Comparison of sepsis-associated acute kidney injury with different degrees and causes reveals patterns in mitochondrial metabolism and immune infiltration changes

Abstract Sepsis-associated acute kidney injury (SA-AKI) is a common complication in critically ill patients, characterized by high morbidity and mortality rates. It remains primarily treated with supportive and nonspecific therapies because of the absence of effective diagnostic biomarkers and thera...

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Bibliographic Details
Main Authors: Nan Yuan, Jianwen Chen, Feng Luo, Zhenyu Fang, Mengjie Huang, Jiaona Liu, Xiangmei Chen, Congjuan Luo
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Sepsis-associated acute kidney injury
Molecular mechanism
Mitochondria
Metabolism
Immune infiltration
Bioinformatics analysis
Online Access:https://doi.org/10.1038/s41598-025-08192-y
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