Circulating T cell atlas in Moyamoya disease: insights into immunopathogenesis of cerebrovascular disorders

Circulating T cell atlas in Moyamoya disease: insights into immunopathogenesis of cerebrovascular disorders

Abstract Background Moyamoya disease (MMD) is a chronic cerebrovascular disorder characterized by progressive stenosis or occlusion of the intracranial arteries, accompanied by the formation of fragile collateral vessels, ultimately leading to ischemic or hemorrhagic strokes. Immune dysregulation, p...

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Main Authors: Chenglong Liu, Junsheng Li, Siqi Mou, Yuheng Pang, Liujia Chan, Qiheng He, Wei Liu, Zhikang Zhao, Bojian Zhang, Zhiyao Zheng, Wei Sun, Xiangjun Shi, Qian Zhang, Rong Wang, Yan Zhang, Wenjing Wang, Dong Zhang, Peicong Ge
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Neuroinflammation
Subjects:
Moyamoya disease
T cells
Mitochondrial dysfunction
Immunometabolism
Mass cytometry
Online Access:https://doi.org/10.1186/s12974-025-03479-3
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