Molecular Subtypes and Targeted Therapeutic Strategies in Small Cell Lung Cancer: Advances, Challenges, and Future Perspectives

Molecular Subtypes and Targeted Therapeutic Strategies in Small Cell Lung Cancer: Advances, Challenges, and Future Perspectives

Small cell lung cancer (SCLC) is a highly aggressive malignancy characterized by rapid progression, early metastasis, and high recurrence rates. Historically considered a homogeneous disease, recent multi-omic studies have revealed distinct molecular subtypes driven by lineage-defining transcription...

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Bibliographic Details
Main Authors: Daoyuan Huang, Jingchao Wang, Li Chen, Weiwei Jiang, Hiroyuki Inuzuka, David K. Simon, Wenyi Wei
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Molecules
Subjects:
SCLC
therapeutic
immune checkpoint
POU2F3
ASCL1
NEUROD1
Online Access:https://www.mdpi.com/1420-3049/30/8/1731
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