Rosuvastatin Counteracts Vessel Arterialisation and Sinusoid Capillarisation, Reduces Tumour Growth, and Prolongs Survival in Murine Hepatocellular Carcinoma

Background and Aims. An arterial blood supply and phenotypic changes of the sinusoids characterise the liver vasculature in human hepatocellular carcinoma (HCC). We investigated the effects of rosuvastatin on liver vessel anomalies, tumour growth and survival in HCC. Methods. We treated transgenic m...

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Bibliographic Details
Main Authors: Annemilaï Tijeras-Raballand, Patricia Hainaud-Hakim, Jean-Olivier Contreres, Caroline Gest, Carole Le Henaff, Bernard I Levy, Marc Pocard, Claudine Soria, Evelyne Dupuy
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2010/640797
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