Federated SPARQL query performance evaluation for exploring disease model mouse: combining gene expression, orthology, and disease knowledge graphs

Federated SPARQL query performance evaluation for exploring disease model mouse: combining gene expression, orthology, and disease knowledge graphs

Abstract Background The RIKEN BRC develops and maintains the RIKEN BioResource MetaDatabase to help users explore appropriate target bioresources for their experiments and prepare precise and high-quality data infrastructures. The Swiss Institute of Bioinformatics develops two databases across multi...

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Bibliographic Details
Main Authors: Tatsuya Kushida, Tarcisio Mendes de Farias, Ana C. Sima, Christophe Dessimoz, Hirokazu Chiba, Frederic B. Bastian, Hiroshi Masuya
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Medical Informatics and Decision Making
Subjects:
Database integration
Gene-disease association
Gene expression
Knowledge graph
Model organism
Ontology
Online Access:https://doi.org/10.1186/s12911-025-03013-8
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