Evaluation of GABAergic Transmission Modulation as a Novel Functional Target for Management of Multiple Sclerosis: Exploring Inhibitory Effect of GABA on Glutamate-Mediated Excitotoxicity
Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system (CNS) where the communication ability of nerve cells in the brain and spinal cord with each other gets impaired. Some current findings suggest the role of glutamate excitotoxicity in the development and progr...
Saved in:
Main Authors: | Ankit A. Gilani, Ranjeet Prasad Dash, Mehul N. Jivrajani, Sandeep Kumar Thakur, Manish Nivsarkar |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
|
Series: | Advances in Pharmacological Sciences |
Online Access: | http://dx.doi.org/10.1155/2014/632376 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Abnormalities in Glutamate Metabolism and Excitotoxicity in the Retinal Diseases
by: Makoto Ishikawa
Published: (2013-01-01) -
Hyperhomocisteinemia, hypercysteinemia, glutamate excitotoxicity, taurine deficiency at hepatitis C
by: V. K. Pozdeev, et al.
Published: (2015-07-01) -
Mixed representations of choice direction and outcome by GABA/glutamate cotransmitting neurons in the entopeduncular nucleus
by: Julianna Locantore, et al.
Published: (2025-01-01) -
Maturation of the GABAergic Transmission in Normal and Pathologic Motoneurons
by: Anne-Emilie Allain, et al.
Published: (2011-01-01) -
Editorial: Cellular and molecular mechanisms that govern assembly, plasticity, and function of GABAergic inhibitory circuits in the mammalian brain
by: Yasufumi Hayano, et al.
Published: (2025-02-01)