Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis

Cell migration is a key process in the shaping and formation of tissues. During sprouting angiogenesis, endothelial tip cells invade avascular tissues by generating actomyosin-dependent forces that drive cell migration and vascular expansion. Surprisingly, endothelial cells (ECs) can still invade if...

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Bibliographic Details
Main Authors: Igor Kondrychyn, Liqun He, Haymar Wint, Christer Betsholtz, Li-Kun Phng
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/98612
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