Trimetazidine stimulates intracellular Ca2+ transients and zebrafish locomotor activity in spinal neurons
Abstract The metabolic modulator trimetazidine (TMZ) is an antianginal recently found to improve skeletal muscle performance in mice models of sarcopenia and of amyotrophic lateral sclerosis (ALS). The mechanism underlying the effect of TMZ on locomotor activity has been proposed to rely on its abil...
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| Main Authors: | Sara Bernardi, Sara Vitolo, Chiara Gabellini, Maria Marchese, Elisabetta Ferraro |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-06065-y |
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