S-Equol, a Major Isoflavone from Soybean, Inhibits Nitric Oxide Production in Lipopolysaccharide-Stimulated Rat Astrocytes Partially via the GPR30-Mediated Pathway

Cumulative evidence indicates that estrogen receptor (ER) agonists attenuate neuroinflammation. Equol, a major isoflavone from soybean, exhibits estrogen-like biological activity, but their effect on inflammatory response has not been well established. Here, we investigated the effect of S-equol on...

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Bibliographic Details
Main Authors: Mitsuaki Moriyama, Ayano Hashimoto, Hideyo Satoh, Kenji Kawabe, Mizue Ogawa, Katsura Takano, Yoichi Nakamura
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/2018/8496973
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