Successful treatment of severe acrodermatitis continua of hallopeau with Bimekizumab: A case report
Acrodermatitis continua of Hallopeau is a rare form of pustular psoriasis affecting the acral fingers and toes, characterized by recurrent eruptions of sterile pustules that lead to significant pain and potentially irreversible destruction of the nail apparatus. Symptoms are often refractory to topi...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-01-01
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| Series: | SAGE Open Medical Case Reports |
| Online Access: | https://doi.org/10.1177/2050313X241311043 |
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| author | Lily Xu Kaiyang Li Eric Mutter Annie Langley |
| author_facet | Lily Xu Kaiyang Li Eric Mutter Annie Langley |
| author_sort | Lily Xu |
| collection | DOAJ |
| description | Acrodermatitis continua of Hallopeau is a rare form of pustular psoriasis affecting the acral fingers and toes, characterized by recurrent eruptions of sterile pustules that lead to significant pain and potentially irreversible destruction of the nail apparatus. Symptoms are often refractory to topical and systemic therapies for psoriasis. This case report presents a healthy 23-year-old female with severe acrodermatitis continua of Hallopeau, destructing all 10 fingernails. Treatment with Bimekizumab, a monoclonal antibody that inhibits interleukin-17, led to 50% improvement by 2 months, and complete normal regrowth of all fingernails by 1 year. The medication was tolerated well without any reported side effects. This is the second reported case of successful acrodermatitis continua of Hallopeau treatment with Bimekizumab, highlighting its potential as an effective and safe option for this challenging and recalcitrant condition. |
| format | Article |
| id | doaj-art-cfa70927b942402288eac91a6f60318c |
| institution | Kabale University |
| issn | 2050-313X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | SAGE Open Medical Case Reports |
| spelling | doaj-art-cfa70927b942402288eac91a6f60318c2025-01-23T06:03:33ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2025-01-011310.1177/2050313X241311043Successful treatment of severe acrodermatitis continua of hallopeau with Bimekizumab: A case reportLily Xu0Kaiyang Li1Eric Mutter2Annie Langley3Family Medicine, Sioux Lookout Meno-Ya-Win Health Center, Sioux Lookout, ON, CanadaFaculty of Medicine and Health Sciences, McGill University, Montreal, QC, CanadaFaculty of Medicine, Division of Emergency Medicine, University of Ottawa, Ottawa, ON, CanadaFaculty of Medicine, Division of Dermatology, University of Ottawa, Ottawa, ON, CanadaAcrodermatitis continua of Hallopeau is a rare form of pustular psoriasis affecting the acral fingers and toes, characterized by recurrent eruptions of sterile pustules that lead to significant pain and potentially irreversible destruction of the nail apparatus. Symptoms are often refractory to topical and systemic therapies for psoriasis. This case report presents a healthy 23-year-old female with severe acrodermatitis continua of Hallopeau, destructing all 10 fingernails. Treatment with Bimekizumab, a monoclonal antibody that inhibits interleukin-17, led to 50% improvement by 2 months, and complete normal regrowth of all fingernails by 1 year. The medication was tolerated well without any reported side effects. This is the second reported case of successful acrodermatitis continua of Hallopeau treatment with Bimekizumab, highlighting its potential as an effective and safe option for this challenging and recalcitrant condition.https://doi.org/10.1177/2050313X241311043 |
| spellingShingle | Lily Xu Kaiyang Li Eric Mutter Annie Langley Successful treatment of severe acrodermatitis continua of hallopeau with Bimekizumab: A case report SAGE Open Medical Case Reports |
| title | Successful treatment of severe acrodermatitis continua of hallopeau with Bimekizumab: A case report |
| title_full | Successful treatment of severe acrodermatitis continua of hallopeau with Bimekizumab: A case report |
| title_fullStr | Successful treatment of severe acrodermatitis continua of hallopeau with Bimekizumab: A case report |
| title_full_unstemmed | Successful treatment of severe acrodermatitis continua of hallopeau with Bimekizumab: A case report |
| title_short | Successful treatment of severe acrodermatitis continua of hallopeau with Bimekizumab: A case report |
| title_sort | successful treatment of severe acrodermatitis continua of hallopeau with bimekizumab a case report |
| url | https://doi.org/10.1177/2050313X241311043 |
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