Patient Specific Dosimetry Phantoms Using Multichannel LDDMM of the Whole Body
This paper describes an automated procedure for creating detailed patient-specific pediatric dosimetry phantoms from a small set of segmented organs in a child's CT scan. The algorithm involves full body mappings from adult template to pediatric images using multichannel large deformation diffe...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | International Journal of Biomedical Imaging |
| Online Access: | http://dx.doi.org/10.1155/2011/481064 |
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| Summary: | This paper describes an automated procedure for creating detailed patient-specific
pediatric dosimetry phantoms from a small set of segmented organs in a child's CT
scan. The algorithm involves full body mappings from adult template to pediatric
images using multichannel large deformation diffeomorphic metric mapping (MC-LDDMM). The parallel implementation and performance of MC-LDDMM for this application is studied here for a sample of 4 pediatric patients, and from 1 to 24
processors. 93.84% of computation time is parallelized, and the efficiency of parallelization remains high until more than 8 processors are used. The performance of the algorithm was validated on a set of 24 male and 18 female pediatric patients. It
was found to be accurate typically to within 1-2 voxels (2–4 mm) and robust across
this large and variable data set. |
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| ISSN: | 1687-4188 1687-4196 |