Comparable efficacy of generic and original alginate for symptom control in PPI-refractory GERD

Comparable efficacy of generic and original alginate for symptom control in PPI-refractory GERD

Abstract Gastroesophageal reflux disease (GERD) is a prevalent global condition, affecting 18.1–27.8% of North Americans and 6.3–18.3% of the Thai population. While proton pump inhibitors (PPIs) are the first-line treatment, only about one-third of patients achieve adequate symptom control. Alginate...

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Main Authors: Kawin Tangvoraphonkchai, Witsarut Manasirisuk, Tanya Apichatvullop, Supatra Srikhajonjit, Manoon Mitpracha, Pattarakorn Promsen, Nutchanun Preechakawin, Khaimook Onthaisong
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Gastroesophageal reflux disease
Generic alginate
Original alginate
Proton pump inhibitors
Reflux disease questionnaire
Online Access:https://doi.org/10.1038/s41598-025-13400-w
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