The Spectrum of Fundus Autofluorescence Findings in Birdshot Chorioretinopathy

Objective. To describe the diverse patterns observed with the use of autofluorescence fundus photography (FAF) in patients with Birdshot chorioretinopathy (BSCR). Methods. A chart review of patients with BSCR seen at the Massachusetts Eye Research and Surgery Institution, who had autofluorescence fu...

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Main Authors: GianPaolo Giuliari, David M. Hinkle, C. Stephen Foster
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2009/567693
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author GianPaolo Giuliari
David M. Hinkle
C. Stephen Foster
author_facet GianPaolo Giuliari
David M. Hinkle
C. Stephen Foster
author_sort GianPaolo Giuliari
collection DOAJ
description Objective. To describe the diverse patterns observed with the use of autofluorescence fundus photography (FAF) in patients with Birdshot chorioretinopathy (BSCR). Methods. A chart review of patients with BSCR seen at the Massachusetts Eye Research and Surgery Institution, who had autofluorescence fundus photography. The data obtained included age, gender, presence of the HLA-A29 haplotype, and current treatment. Results. Eighteen eyes with HLA-A29 associated BSCR were included. Four eyes presented with active inflammation. Correspondence of the lesions noted in the colour fundus photograph was observed in 3 eyes which were more easily identified with the FAF. Fifteen eyes had fundus lesions more numerous and evident in the FAF than in the colour fundus photograph. Conclusion. Because FAF testing provides valuable insight into the metabolic state of the PR/RPE-complex, it may serve as a useful noninvasive assessment tool in patients with posterior uveitis in which the outer retina-RPE-choriocapillaries-complex is involved.
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spelling doaj-art-cf99e8be13b14f30876f0034bd824db12025-02-03T07:25:47ZengWileyJournal of Ophthalmology2090-004X2090-00582009-01-01200910.1155/2009/567693567693The Spectrum of Fundus Autofluorescence Findings in Birdshot ChorioretinopathyGianPaolo Giuliari0David M. Hinkle1C. Stephen Foster2Massachusetts Eye Research and Surgery Institution, Cambridge, MA 02142, USAMassachusetts Eye Research and Surgery Institution, Cambridge, MA 02142, USAMassachusetts Eye Research and Surgery Institution, Cambridge, MA 02142, USAObjective. To describe the diverse patterns observed with the use of autofluorescence fundus photography (FAF) in patients with Birdshot chorioretinopathy (BSCR). Methods. A chart review of patients with BSCR seen at the Massachusetts Eye Research and Surgery Institution, who had autofluorescence fundus photography. The data obtained included age, gender, presence of the HLA-A29 haplotype, and current treatment. Results. Eighteen eyes with HLA-A29 associated BSCR were included. Four eyes presented with active inflammation. Correspondence of the lesions noted in the colour fundus photograph was observed in 3 eyes which were more easily identified with the FAF. Fifteen eyes had fundus lesions more numerous and evident in the FAF than in the colour fundus photograph. Conclusion. Because FAF testing provides valuable insight into the metabolic state of the PR/RPE-complex, it may serve as a useful noninvasive assessment tool in patients with posterior uveitis in which the outer retina-RPE-choriocapillaries-complex is involved.http://dx.doi.org/10.1155/2009/567693
spellingShingle GianPaolo Giuliari
David M. Hinkle
C. Stephen Foster
The Spectrum of Fundus Autofluorescence Findings in Birdshot Chorioretinopathy
Journal of Ophthalmology
title The Spectrum of Fundus Autofluorescence Findings in Birdshot Chorioretinopathy
title_full The Spectrum of Fundus Autofluorescence Findings in Birdshot Chorioretinopathy
title_fullStr The Spectrum of Fundus Autofluorescence Findings in Birdshot Chorioretinopathy
title_full_unstemmed The Spectrum of Fundus Autofluorescence Findings in Birdshot Chorioretinopathy
title_short The Spectrum of Fundus Autofluorescence Findings in Birdshot Chorioretinopathy
title_sort spectrum of fundus autofluorescence findings in birdshot chorioretinopathy
url http://dx.doi.org/10.1155/2009/567693
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