Rhabdomyolysis Induced by Nonstrenuous Exercise in a Patient with Graves’ Disease
Hyperthyroidism can result in several musculoskeletal conditions such as thyrotoxic periodic paralysis, thyrotoxic myopathy, and thyroid ophthalmopathy. Rhabdomyolysis has been rarely reported to be associated with hyperthyroidism. We describe a 33-year-old man who presented with bilateral thigh pai...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2014/286450 |
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| author | Sarawut Summachiwakij Issac Sachmechi |
| author_facet | Sarawut Summachiwakij Issac Sachmechi |
| author_sort | Sarawut Summachiwakij |
| collection | DOAJ |
| description | Hyperthyroidism can result in several musculoskeletal conditions such as thyrotoxic periodic paralysis, thyrotoxic myopathy, and thyroid ophthalmopathy. Rhabdomyolysis has been rarely reported to be associated with hyperthyroidism. We describe a 33-year-old man who presented with bilateral thigh pain and dark brown urine after regular squatting. He had a past medical history of hyperthyroidism but stopped taking it 2 months prior to admission. He was found to have rhabdomyolysis, myoglobinuria, and thyrotoxicosis. Presence of thyroid-stimulating immunoglobulins (TSI) and high radioiodine uptake confirmed a diagnosis of Graves' disease. He received aggressive fluid resuscitation and sodium bicarbonate intravenously along with monitoring fluid and electrolyte. Methimazole was also resumed. The patient responded to treatment and rhabdomyolysis gradually resolved. Therefore, nonstrenuous exercise can potentially induce rhabdomyolysis in patients with hyperthyroidism. Although hyperthyroidism is not widely recognized as a cause of rhabdomyolysis, it should be considered in the differential diagnosis of rhabdomyolysis. |
| format | Article |
| id | doaj-art-cf960780753b42b7963d454c247424e3 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-cf960780753b42b7963d454c247424e32025-02-03T01:23:16ZengWileyCase Reports in Endocrinology2090-65012090-651X2014-01-01201410.1155/2014/286450286450Rhabdomyolysis Induced by Nonstrenuous Exercise in a Patient with Graves’ DiseaseSarawut Summachiwakij0Issac Sachmechi1Department of Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, New York, NY 11432, USADivision of Endocrinology, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, New York, NY 11432, USAHyperthyroidism can result in several musculoskeletal conditions such as thyrotoxic periodic paralysis, thyrotoxic myopathy, and thyroid ophthalmopathy. Rhabdomyolysis has been rarely reported to be associated with hyperthyroidism. We describe a 33-year-old man who presented with bilateral thigh pain and dark brown urine after regular squatting. He had a past medical history of hyperthyroidism but stopped taking it 2 months prior to admission. He was found to have rhabdomyolysis, myoglobinuria, and thyrotoxicosis. Presence of thyroid-stimulating immunoglobulins (TSI) and high radioiodine uptake confirmed a diagnosis of Graves' disease. He received aggressive fluid resuscitation and sodium bicarbonate intravenously along with monitoring fluid and electrolyte. Methimazole was also resumed. The patient responded to treatment and rhabdomyolysis gradually resolved. Therefore, nonstrenuous exercise can potentially induce rhabdomyolysis in patients with hyperthyroidism. Although hyperthyroidism is not widely recognized as a cause of rhabdomyolysis, it should be considered in the differential diagnosis of rhabdomyolysis.http://dx.doi.org/10.1155/2014/286450 |
| spellingShingle | Sarawut Summachiwakij Issac Sachmechi Rhabdomyolysis Induced by Nonstrenuous Exercise in a Patient with Graves’ Disease Case Reports in Endocrinology |
| title | Rhabdomyolysis Induced by Nonstrenuous Exercise in a Patient with Graves’ Disease |
| title_full | Rhabdomyolysis Induced by Nonstrenuous Exercise in a Patient with Graves’ Disease |
| title_fullStr | Rhabdomyolysis Induced by Nonstrenuous Exercise in a Patient with Graves’ Disease |
| title_full_unstemmed | Rhabdomyolysis Induced by Nonstrenuous Exercise in a Patient with Graves’ Disease |
| title_short | Rhabdomyolysis Induced by Nonstrenuous Exercise in a Patient with Graves’ Disease |
| title_sort | rhabdomyolysis induced by nonstrenuous exercise in a patient with graves disease |
| url | http://dx.doi.org/10.1155/2014/286450 |
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