Endocrine and metabolic alterations in response to systemic inflammation and sepsis: a review article

Endocrine and metabolic alterations in response to systemic inflammation and sepsis: a review article

Abstract Severe sepsis is cognate with life threatening multi-organ dysfunction. There is a disturbance in endocrine functions with alterations in several hormonal pathways. It has frequently been linked with dysfunction in the hypothalamic pituitary-adrenal axis (HPA). Increased cortisol or cortiso...

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Main Authors: Syed Faizan Mehdi, Muhammad Hamza Qureshi, Salman Pervaiz, Karishma Kumari, Edwin Saji, Mahnoor Shah, Ahmad Abdullah, Kamran Zahoor, Hafiza Amna Qadeer, Disha Kumari Katari, Christine Metz, Lopa Mishra, Derek LeRoith, Kevin Tracey, Michael J. Brownstein, Jesse Roth
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Medicine
Subjects:
Inflammation
Sepsis
Septic shock
Metabolism
Hormones
Endocrine
Online Access:https://doi.org/10.1186/s10020-025-01074-z
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