Blood eosinophils and serum eosinophil cationic protein in patients with acute and chronic urticaria
We have analysed the relationship of blood eosinophil count and serum eosinophil cationic protein (ECP) levels in patients with acute and chronic idiopathic urticaria. The ECP levels and eosinophil counts were measured in the peripheral blood of 15 patients with acute urticaria, 25 with chronic idio...
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| Format: | Article |
| Language: | English |
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Wiley
1996-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/S0962935196000191 |
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| author | G. Di Lorenzo P. Mansueto M. Melluso G. Candore D. Cigna M. E. Pellitteri A. Di Salvo C. Caruso |
| author_facet | G. Di Lorenzo P. Mansueto M. Melluso G. Candore D. Cigna M. E. Pellitteri A. Di Salvo C. Caruso |
| author_sort | G. Di Lorenzo |
| collection | DOAJ |
| description | We have analysed the relationship of blood eosinophil count and serum eosinophil cationic protein (ECP) levels in patients with acute and chronic idiopathic urticaria. The ECP levels and eosinophil counts were measured in the peripheral blood of 15 patients with acute urticaria, 25 with chronic idiopathic urticaria and 10 normal healthy subjects. Blood eosinophil counts and serum ECP levels increased in all patients with acute urticaria. Concerning patients affected by chronic urticaria, taking into account the recrudescence of the disease at the moment of taking the blood sample, only symptomatic patients showed increased eosinophil blood values whereas serum ECP levels were increased both in symptomatic and asymptomatic patients. Furthermore, serum ECP levels in chronic urticaria did not correlate with the peripheral eosinophil counts, as they did in acute urticaria. The results of the present study indicate that eosinophils may play a role in the inflammatory mechanisms in patients with acute and chronic urticaria showing a positive correlation between serum ECP levels and disease activity. |
| format | Article |
| id | doaj-art-cf4bf3ff9c854a1e817fb8b064fea020 |
| institution | OA Journals |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 1996-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-cf4bf3ff9c854a1e817fb8b064fea0202025-08-20T02:20:09ZengWileyMediators of Inflammation0962-93511466-18611996-01-015211311510.1155/S0962935196000191Blood eosinophils and serum eosinophil cationic protein in patients with acute and chronic urticariaG. Di Lorenzo0P. Mansueto1M. Melluso2G. Candore3D. Cigna4M. E. Pellitteri5A. Di Salvo6C. Caruso7Cattedra di Medicina Interna II, Istituto di Medicina Interna e Geriatria, ItalyCattedra di Medicina Interna II, Istituto di Medicina Interna e Geriatria, ItalyCattedra di Medicina Interna II, Istituto di Medicina Interna e Geriatria, ItalyServizio di Tipizzazione Tissutale, Istituto di Patologia generale, Università di Palermo, Corso Tukory 211, Palermo 90134, ItalyServizio di Tipizzazione Tissutale, Istituto di Patologia generale, Università di Palermo, Corso Tukory 211, Palermo 90134, ItalyCattedra di Medicina Interna II, Istituto di Medicina Interna e Geriatria, ItalyCattedra di Medicina Interna II, Istituto di Medicina Interna e Geriatria, ItalyServizio di Tipizzazione Tissutale, Istituto di Patologia generale, Università di Palermo, Corso Tukory 211, Palermo 90134, ItalyWe have analysed the relationship of blood eosinophil count and serum eosinophil cationic protein (ECP) levels in patients with acute and chronic idiopathic urticaria. The ECP levels and eosinophil counts were measured in the peripheral blood of 15 patients with acute urticaria, 25 with chronic idiopathic urticaria and 10 normal healthy subjects. Blood eosinophil counts and serum ECP levels increased in all patients with acute urticaria. Concerning patients affected by chronic urticaria, taking into account the recrudescence of the disease at the moment of taking the blood sample, only symptomatic patients showed increased eosinophil blood values whereas serum ECP levels were increased both in symptomatic and asymptomatic patients. Furthermore, serum ECP levels in chronic urticaria did not correlate with the peripheral eosinophil counts, as they did in acute urticaria. The results of the present study indicate that eosinophils may play a role in the inflammatory mechanisms in patients with acute and chronic urticaria showing a positive correlation between serum ECP levels and disease activity.http://dx.doi.org/10.1155/S0962935196000191 |
| spellingShingle | G. Di Lorenzo P. Mansueto M. Melluso G. Candore D. Cigna M. E. Pellitteri A. Di Salvo C. Caruso Blood eosinophils and serum eosinophil cationic protein in patients with acute and chronic urticaria Mediators of Inflammation |
| title | Blood eosinophils and serum eosinophil cationic protein in patients with acute and chronic urticaria |
| title_full | Blood eosinophils and serum eosinophil cationic protein in patients with acute and chronic urticaria |
| title_fullStr | Blood eosinophils and serum eosinophil cationic protein in patients with acute and chronic urticaria |
| title_full_unstemmed | Blood eosinophils and serum eosinophil cationic protein in patients with acute and chronic urticaria |
| title_short | Blood eosinophils and serum eosinophil cationic protein in patients with acute and chronic urticaria |
| title_sort | blood eosinophils and serum eosinophil cationic protein in patients with acute and chronic urticaria |
| url | http://dx.doi.org/10.1155/S0962935196000191 |
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