FOXA3, a Negative Regulator of Nur77 Expression and Activity in Testicular Steroidogenesis

Biosynthesis of testosterone occurs mainly in the testicular Leydig cells. Nur77, an orphan nuclear receptor that is expressed in response to the luteinizing hormone/cyclic adenosine monophosphate (LH/cAMP) signaling pathway, is one of the key factors that regulate steroidogenesis in Leydig cells. T...

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Bibliographic Details
Main Authors: Hansle Kim, Sudeep Kumar, Keesook Lee
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2021/6619447
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