FOXA3, a Negative Regulator of Nur77 Expression and Activity in Testicular Steroidogenesis
Biosynthesis of testosterone occurs mainly in the testicular Leydig cells. Nur77, an orphan nuclear receptor that is expressed in response to the luteinizing hormone/cyclic adenosine monophosphate (LH/cAMP) signaling pathway, is one of the key factors that regulate steroidogenesis in Leydig cells. T...
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Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-01-01
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Series: | International Journal of Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2021/6619447 |
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