Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor

Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor

Abstract NUCOLL43 is a novel ovarian clear cell carcinoma (O‐CCC) cell line that arose from a primary culture of a patient's malignant ascites. The cells grow reliably in cell culture with a doubling time of approx. 45 hours and form colonies at high efficiency. They have a very high degree of...

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Bibliographic Details
Main Authors: Miriam Franklin, Lucy Gentles, Elizabeth Matheson, Nick Bown, Paul Cross, Angela Ralte, Connor Gilkes‐Immeson, Alice Bradbury, Maryam Zanjirband, John Lunec, Yvette Drew, Rachel O'Donnell, Nicola J. Curtin
Format: Article
Language:English
Published: Wiley 2018-09-01
Series:Cancer Medicine
Subjects:
cytotoxic drugs
DNA repair
loss of heterozygosity
new cell line
NVP‐BEZ235
ovarian clear cell carcinoma
Online Access:https://doi.org/10.1002/cam4.1724
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