Role of plasma metabolome in mediating the effect of plasma lipidome on NAFLD: a Mendelian randomization study

Role of plasma metabolome in mediating the effect of plasma lipidome on NAFLD: a Mendelian randomization study

BackgroundThis study explored the causal connection among the plasma lipidome, nonalcoholic fatty liver disease (NAFLD), and potential metabolome mediators through Mendelian randomization (MR).MethodsWe obtained summary statistics for 179 plasma lipidome traits (N = 7,174), 1,400 plasma metabolome t...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhuyuan Zheng, Shaojie Yang, Wanlin Dai, Yang Sun, Jingnan Wang, Xiaolin Zhang, Yiming Zheng, Jing Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Endocrinology
Subjects:
Mendelian randomization (MR)
nonalcoholic fatty liver disease (NAFLD)
plasma lipidome
plasma metabolome
mediation analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1436827/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items