Meta-analysis of uveal melanoma genome-wide association studies identifies novel risk loci and population effect size heterogeneity

Meta-analysis of uveal melanoma genome-wide association studies identifies novel risk loci and population effect size heterogeneity

Summary: Uveal melanoma (UM) is a rare but frequently metastasizing cancer. Genome-wide association studies have identified three common genome-wide significant germline risk loci. Here, we perform a genome-wide association study on 401 new cases and conduct a meta-analysis with three independent pr...

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Bibliographic Details
Main Authors: Georgia Mies, Noah L. Tsao, Alexandre Houy, Sarah E. Coupland, Helen Kalirai, Asta Försti, Kari Hemminki, Hauke Thomsen, Marc-Henri Stern, Carol L. Shields, Scott M. Damrauer, Katheryn G. Ewens, Arupa Ganguly, Iain Mathieson
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:HGG Advances
Subjects:
uveal melanoma
genome-wide association study
eye pigmentation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247725000685
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