Association between opioid use and survival in advanced non small cell lung cancer patients treated with immune checkpoint inhibitors

Association between opioid use and survival in advanced non small cell lung cancer patients treated with immune checkpoint inhibitors

Abstract Cancer-related pain is a frequent challenge among non-small cell lung (NSCLC) cancer patients, particularly for those with advanced disease and/or bone metastases. Opioids are the mainstay of treatment for moderate to severe cancer-related pain. However, emerging lines of evidence suggest t...

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Bibliographic Details
Main Authors: Luigi Liguori, Stefano Pepe, Valentina Pagliara, Rosario De Feo, Alessandro Ottaiano, Francesco Perri, Giovanna Polcaro, Valeria Conti, Cristina R. Ferrone, Francesco Sabbatino, Marco Cascella
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Biomarker
ICI
NSCLC
Opioid
PD-1
Real-world
Online Access:https://doi.org/10.1038/s41598-025-15684-4
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