The role of tumor necrosis factor receptor superfamily in cancer: insights into oncogenesis, progression, and therapeutic strategies

Abstract The TNF receptor superfamily (TNFRSF) with extracellular cysteine-rich domains, transmembrane segments, and intracellular signaling motifs, plays crucial roles in cell death, inflammation, growth, and development. These cysteine-rich domains, which are located in the external portion of the...

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Bibliographic Details
Main Author: Jiayi Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00990-x
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