Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp.
External factors affecting composition of the human gut microbiota have attracted considerable attention in recent years. Among these factors, habitat sharing with other humans and companion animals, especially dogs, is considered crucial together with the presence of intestinal protists. The Czech...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | One Health |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352771425000151 |
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| author | Zuzana Pavlíčková Barbora Pafčo Vladislav Ilík Lee O'Brien Andersen Milan Jirků Kristýna Brožová David Modrý Oldřiška Kadlecová Christen Rune Stensvold Kateřina Jirků |
| author_facet | Zuzana Pavlíčková Barbora Pafčo Vladislav Ilík Lee O'Brien Andersen Milan Jirků Kristýna Brožová David Modrý Oldřiška Kadlecová Christen Rune Stensvold Kateřina Jirků |
| author_sort | Zuzana Pavlíčková |
| collection | DOAJ |
| description | External factors affecting composition of the human gut microbiota have attracted considerable attention in recent years. Among these factors, habitat sharing with other humans and companion animals, especially dogs, is considered crucial together with the presence of intestinal protists. The Czech Republic, known for one of the highest rates of dog ownership in Europe, provides an ideal setting for studying such relationships.Here, we investigated the impact of dog ownership and lifestyle factors (residing in cities versus villages) on the gut microbiota (specifically bacteriome). In addition, we also investigated the influence of the common gut protist Blastocystis sp. on the human gut microbiota. Fecal DNAs from 118 humans and 54 dogs were subject to 16S rRNA gene sequencing using the Illumina MiSeq platform.Greater microbial diversity was observed in humans than in dogs. Owning a dog had no significant effect on the alpha and beta diversity of the human microbiota, although some bacterial genera were enriched in dog owners. In relation to lifestyle, urban dwellers had higher levels of Akkermansia, while people living in villages had a more diverse gut microbiota. The presence of Blastocystis sp. in humans correlated with specific microbial patterns, indicating an important role for this micro-eukaryote in the gut ecosystem.These findings highlight the intricate relationship between specific factors and the gut microbiota composition and emphasize the need for more extensive research in this area. |
| format | Article |
| id | doaj-art-ce9470e8e6244090aac1b7c8b38ae583 |
| institution | Kabale University |
| issn | 2352-7714 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | One Health |
| spelling | doaj-art-ce9470e8e6244090aac1b7c8b38ae5832025-01-30T05:14:25ZengElsevierOne Health2352-77142025-06-0120100979Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp.Zuzana Pavlíčková0Barbora Pafčo1Vladislav Ilík2Lee O'Brien Andersen3Milan Jirků4Kristýna Brožová5David Modrý6Oldřiška Kadlecová7Christen Rune Stensvold8Kateřina Jirků9Institute of Parasitology, Biology Centre, the Czech Academy of Sciences, České Budějovice, Czech Republic; Corresponding author.Institute of Parasitology, Biology Centre, the Czech Academy of Sciences, České Budějovice, Czech Republic; Institute of Vertebrate Biology, Czech Academy of Sciences, Květná 8, Brno, Czech RepublicInstitute of Parasitology, Biology Centre, the Czech Academy of Sciences, České Budějovice, Czech Republic; Institute of Vertebrate Biology, Czech Academy of Sciences, Květná 8, Brno, Czech RepublicDepartment of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, DenmarkInstitute of Parasitology, Biology Centre, the Czech Academy of Sciences, České Budějovice, Czech RepublicInstitute of Parasitology, Biology Centre, the Czech Academy of Sciences, České Budějovice, Czech Republic; Faculty of Science, University of South Bohemia, České Budějovice, Czech RepublicInstitute of Parasitology, Biology Centre, the Czech Academy of Sciences, České Budějovice, Czech Republic; Department of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences, Prague, Czech Republic; Department of Botany and Zoology, Faculty of Science, Masaryk University, Brno, Czech RepublicInstitute of Parasitology, Biology Centre, the Czech Academy of Sciences, České Budějovice, Czech RepublicDepartment of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, DenmarkInstitute of Parasitology, Biology Centre, the Czech Academy of Sciences, České Budějovice, Czech Republic; Faculty of Science, University of South Bohemia, České Budějovice, Czech RepublicExternal factors affecting composition of the human gut microbiota have attracted considerable attention in recent years. Among these factors, habitat sharing with other humans and companion animals, especially dogs, is considered crucial together with the presence of intestinal protists. The Czech Republic, known for one of the highest rates of dog ownership in Europe, provides an ideal setting for studying such relationships.Here, we investigated the impact of dog ownership and lifestyle factors (residing in cities versus villages) on the gut microbiota (specifically bacteriome). In addition, we also investigated the influence of the common gut protist Blastocystis sp. on the human gut microbiota. Fecal DNAs from 118 humans and 54 dogs were subject to 16S rRNA gene sequencing using the Illumina MiSeq platform.Greater microbial diversity was observed in humans than in dogs. Owning a dog had no significant effect on the alpha and beta diversity of the human microbiota, although some bacterial genera were enriched in dog owners. In relation to lifestyle, urban dwellers had higher levels of Akkermansia, while people living in villages had a more diverse gut microbiota. The presence of Blastocystis sp. in humans correlated with specific microbial patterns, indicating an important role for this micro-eukaryote in the gut ecosystem.These findings highlight the intricate relationship between specific factors and the gut microbiota composition and emphasize the need for more extensive research in this area.http://www.sciencedirect.com/science/article/pii/S2352771425000151DogsHumansGut microbiotaDog ownershipLifestyleBlastocystis sp |
| spellingShingle | Zuzana Pavlíčková Barbora Pafčo Vladislav Ilík Lee O'Brien Andersen Milan Jirků Kristýna Brožová David Modrý Oldřiška Kadlecová Christen Rune Stensvold Kateřina Jirků Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp. One Health Dogs Humans Gut microbiota Dog ownership Lifestyle Blastocystis sp |
| title | Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp. |
| title_full | Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp. |
| title_fullStr | Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp. |
| title_full_unstemmed | Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp. |
| title_short | Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and Blastocystis sp. |
| title_sort | shaping the human gut microbiota the role of canine companionship lifestyle choices and blastocystis sp |
| topic | Dogs Humans Gut microbiota Dog ownership Lifestyle Blastocystis sp |
| url | http://www.sciencedirect.com/science/article/pii/S2352771425000151 |
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