Classification, Mechanisms of Action, and Therapeutic Applications of Inhibitory Oligonucleotides for Toll-Like Receptors (TLR) 7 and 9

Classification, Mechanisms of Action, and Therapeutic Applications of Inhibitory Oligonucleotides for Toll-Like Receptors (TLR) 7 and 9

Our immune defense depends on two specialized armed forces. The innate force acts as an alarm mechanism that senses changes in the microenvironment through the recognition of common microbial patterns by Toll-like receptors (TLR) and NOD proteins. It rapidly generates an inflammatory response aimed...

Full description

Saved in:

Bibliographic Details
Main Author:	Petar S. Lenert
Format:	Article
Language:	English
Published:	Wiley 2010-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2010/986596
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Toll-Like Receptor Signaling Pathways—Therapeutic Opportunities
by: Jiankun Zhu, et al.
Published: (2010-01-01)

Toll-like receptors in atopic dermatitis: pathogenesis and therapeutic implications
by: Ahmad Vafaeian, et al.
Published: (2025-02-01)

Modulation of Toll-Like Receptor Signalling as a New Therapeutic Principle
by: Philipp M. Lepper, et al.
Published: (2010-01-01)

Collaborative Action of Toll-Like and Nod-Like Receptors as Modulators of the Inflammatory Response to Pathogenic Bacteria
by: Javier Oviedo-Boyso, et al.
Published: (2014-01-01)

Expression of Toll-Like Receptors 3, 7, and 9 in Peripheral Blood Mononuclear Cells from Patients with Systemic Lupus Erythematosus
by: Agnieszka Klonowska-Szymczyk, et al.
Published: (2014-01-01)

Association of Toll-Like Receptor 2 (TLR2) Expression in Placenta and Intrauterine Exposure to Hepatitis B Virus
by: Dian Utami, et al.
Published: (2022-01-01)

Extracellular Cardiolipin Modulates Select Immune Functions of Astrocytes in Toll-Like Receptor (TLR) 4-Dependent Manner
by: Taryn E. Murray, et al.
Published: (2022-01-01)

Toll-Like Receptor 4: A Promising Therapeutic Target for Alzheimer’s Disease
by: Linyu Wu, et al.
Published: (2022-01-01)

Toll-Like Receptor 9 Promotes Cardiac Inflammation and Heart Failure during Polymicrobial Sepsis
by: Ralph Lohner, et al.
Published: (2013-01-01)

Diverse Profiles of Toll-Like Receptors 2, 4, 7, and 9 mRNA in Peripheral Blood and Biopsy Specimens of Patients with Celiac Disease
by: Haniye Ghasiyari, et al.
Published: (2018-01-01)

3-(5-Hydroxyphenyl)-5-Phenyl-2-Pyrazolines as Toll-Like Receptor 7 Agonists
by: Ji Hwan Kim, et al.
Published: (2023-01-01)

Targeting Toll-Like Receptors for Treatment of SLE
by: Christopher G. Horton, et al.
Published: (2010-01-01)

Toll-Like Receptor Signaling and Liver Fibrosis
by: Tomonori Aoyama, et al.
Published: (2010-01-01)

Association Between Single-Nucleotide Polymorphisms in <i>Toll-like Receptor 3</i> (<i>tlr3</i>), <i>tlr7</i>, <i>tlr8</i> and <i>tirap</i> Genes with Severe Symptoms in Children Presenting COVID-19
by: Adriana Souza Andrade, et al.
Published: (2024-12-01)

Association of Polymorphisms in Toll-Like Receptors 4 and 9 with Autoimmune Thyroid Disease in Korean Pediatric Patients
by: Won Kyoung Cho, et al.
Published: (2017-01-01)

Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
by: Yangchen Dhondup, et al.
Published: (2017-01-01)

pDC Activation by TLR7/8 Ligand CL097 Compared to TLR7 Ligand IMQ or TLR9 Ligand CpG
by: Jing Wu, et al.
Published: (2019-01-01)

Toll-Like Receptors in Hepatic Ischemia/Reperfusion and Transplantation
by: John Evankovich, et al.
Published: (2010-01-01)

Current Views of Toll-Like Receptor Signaling Pathways
by: Masahiro Yamamoto, et al.
Published: (2010-01-01)

TIRAP, TRAM, and Toll-Like Receptors: The Untold Story
by: Valérie Lannoy, et al.
Published: (2023-01-01)

Toll-Like Receptors in Leishmania Infections: Guardians or Promoters?
by: Marilia S. Faria, et al.
Published: (2012-01-01)

Toll-Like Receptor-Based Strategies for Cancer Immunotherapy
by: Saghar Pahlavanneshan, et al.
Published: (2021-01-01)

Genetic Polymorphisms of Toll-like receptors 2 and 9 as Susceptibility Factors for the Development of Ankylosing Spondylitis and Psoriatic Arthritis
by: Camila F. Oliveira-Toré, et al.
Published: (2019-01-01)

Toll-Like Receptors and RIG-I-Like Receptors Play Important Roles in Resisting Flavivirus
by: Hong-Yan Guo, et al.
Published: (2018-01-01)

Modulation of Toll-Like Receptor Activity by Leukocyte Ig-Like Receptors and Their Effects during Bacterial Infection
by: Louise E. Pilsbury, et al.
Published: (2010-01-01)

Toll-Like Receptors Expression and Signaling in Glia Cells in Neuro-Amyloidogenic Diseases: Towards Future Therapeutic Application
by: Dorit Trudler, et al.
Published: (2010-01-01)

Toll-Like Receptor 4 Activation in Cancer Progression and Therapy
by: Alja Oblak, et al.
Published: (2011-01-01)

The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation
by: Monica Molteni, et al.
Published: (2016-01-01)

The Role of Toll-Like Receptor Signaling in the Progression of Heart Failure
by: Lili Yu, et al.
Published: (2018-01-01)

Toll-Like Receptors in Natural Killer Cells and Their Application for Immunotherapy
by: Ji-Yoon Noh, et al.
Published: (2020-01-01)

Different Pathological Roles of Toll-Like Receptor 9 on Mucosal B Cells and Dendritic Cells in Murine IgA Nephropathy
by: Tadahiro Kajiyama, et al.
Published: (2011-01-01)

The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis
by: Mohsin H. K. Roshan, et al.
Published: (2016-01-01)

Acid sphingomyelinase modulates anxiety-like behavior likely through toll-like receptor signaling pathway
by: Huiqi Yuan, et al.
Published: (2025-02-01)

Inflammatory Role of Toll-Like Receptors in Human and Murine Adipose Tissue
by: Odile Poulain-Godefroy, et al.
Published: (2010-01-01)

TNIP1 in Autoimmune Diseases: Regulation of Toll-like Receptor Signaling
by: Rambon Shamilov, et al.
Published: (2018-01-01)

Role of Cytokines and Toll-Like Receptors in the Immunopathogenesis of Guillain-Barré Syndrome
by: Kishan Kumar Nyati, et al.
Published: (2014-01-01)

Immunomodulation by Gut Microbiota: Role of Toll-Like Receptor Expressed by T Cells
by: Mariagrazia Valentini, et al.
Published: (2014-01-01)

Genetic Diversity of Toll-Like Receptors and Immunity to M. leprae Infection
by: Bryan E. Hart, et al.
Published: (2012-01-01)

Toll-like receptor 4 pathway evolutionary trajectory and functional emergence
by: Shailya Verma, et al.
Published: (2025-01-01)

Evidence for Activation of Toll-Like Receptor and Receptor for Advanced Glycation End Products in Preterm Birth
by: Taketoshi Noguchi, et al.
Published: (2010-01-01)