Acute Ischemic Stroke Secondary to Iron Deficiency Anemia: A Case Report

A rare case of acute ischemic stroke in a young patient with iron deficiency anemia (IDA) is reported. IDA has been suggested to have an association with stroke, but few cases have proven it thus far. Three physiological mechanisms explaining IDA to ischemic stroke include a hypercoagulable state se...

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Main Authors: Preema J. Mehta, Sherita Chapman, Annapurni Jayam-Trouth, Mohankumar Kurukumbi
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2012/487080
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author Preema J. Mehta
Sherita Chapman
Annapurni Jayam-Trouth
Mohankumar Kurukumbi
author_facet Preema J. Mehta
Sherita Chapman
Annapurni Jayam-Trouth
Mohankumar Kurukumbi
author_sort Preema J. Mehta
collection DOAJ
description A rare case of acute ischemic stroke in a young patient with iron deficiency anemia (IDA) is reported. IDA has been suggested to have an association with stroke, but few cases have proven it thus far. Three physiological mechanisms explaining IDA to ischemic stroke include a hypercoagulable state secondary to IDA, thrombocytosis secondary to IDA, and anemic hypoxia induced by IDA. Our paper shows an example of a hypoxia-induced stroke secondary to IDA in a young woman with menorrhagia. Thrombus formation was ruled out as the Magnetic Resonance Angiogram (MRA) showed no evidence. As all other known causes for stroke were ruled out, the patient's IDA is a reasonable cause for her stroke. Iron deficiency decreases the amount of hemoglobin, which consequently decreases the amount of oxygen in the blood resulting in low-oxygen delivery to the brain. This causes hypoxic conditions in the brain, leading to death of brain tissue. Thus, we suggest a possible relationship between IDA and ischemic stroke in young adults. Considering IDA as one of the risk factors for ischemic stroke and treating with timely transfusions would be an important step one can take to prevent stroke.
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spelling doaj-art-ce86b49343624364b888e12b44049dac2025-02-03T05:58:44ZengWileyCase Reports in Neurological Medicine2090-66682090-66762012-01-01201210.1155/2012/487080487080Acute Ischemic Stroke Secondary to Iron Deficiency Anemia: A Case ReportPreema J. Mehta0Sherita Chapman1Annapurni Jayam-Trouth2Mohankumar Kurukumbi3Department of Neurology, Howard University Hospital, 2041 Georgia Ave., Washington, DC 20060, USADepartment of Neurology, Howard University Hospital, 2041 Georgia Ave., Washington, DC 20060, USADepartment of Neurology, Howard University Hospital, 2041 Georgia Ave., Washington, DC 20060, USADepartment of Neurology, Howard University Hospital, 2041 Georgia Ave., Washington, DC 20060, USAA rare case of acute ischemic stroke in a young patient with iron deficiency anemia (IDA) is reported. IDA has been suggested to have an association with stroke, but few cases have proven it thus far. Three physiological mechanisms explaining IDA to ischemic stroke include a hypercoagulable state secondary to IDA, thrombocytosis secondary to IDA, and anemic hypoxia induced by IDA. Our paper shows an example of a hypoxia-induced stroke secondary to IDA in a young woman with menorrhagia. Thrombus formation was ruled out as the Magnetic Resonance Angiogram (MRA) showed no evidence. As all other known causes for stroke were ruled out, the patient's IDA is a reasonable cause for her stroke. Iron deficiency decreases the amount of hemoglobin, which consequently decreases the amount of oxygen in the blood resulting in low-oxygen delivery to the brain. This causes hypoxic conditions in the brain, leading to death of brain tissue. Thus, we suggest a possible relationship between IDA and ischemic stroke in young adults. Considering IDA as one of the risk factors for ischemic stroke and treating with timely transfusions would be an important step one can take to prevent stroke.http://dx.doi.org/10.1155/2012/487080
spellingShingle Preema J. Mehta
Sherita Chapman
Annapurni Jayam-Trouth
Mohankumar Kurukumbi
Acute Ischemic Stroke Secondary to Iron Deficiency Anemia: A Case Report
Case Reports in Neurological Medicine
title Acute Ischemic Stroke Secondary to Iron Deficiency Anemia: A Case Report
title_full Acute Ischemic Stroke Secondary to Iron Deficiency Anemia: A Case Report
title_fullStr Acute Ischemic Stroke Secondary to Iron Deficiency Anemia: A Case Report
title_full_unstemmed Acute Ischemic Stroke Secondary to Iron Deficiency Anemia: A Case Report
title_short Acute Ischemic Stroke Secondary to Iron Deficiency Anemia: A Case Report
title_sort acute ischemic stroke secondary to iron deficiency anemia a case report
url http://dx.doi.org/10.1155/2012/487080
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AT sheritachapman acuteischemicstrokesecondarytoirondeficiencyanemiaacasereport
AT annapurnijayamtrouth acuteischemicstrokesecondarytoirondeficiencyanemiaacasereport
AT mohankumarkurukumbi acuteischemicstrokesecondarytoirondeficiencyanemiaacasereport