Imaging Software-Based Sarcopenia Assessment in Gastroenterology: Evolution and Clinical Meaning

Sarcopenia is gaining attention as a negative prognostic factor in different fields of medicine, including chronic liver failure. However, the assessment of sarcopenia in patients with liver diseases is often neglected due to unawareness of reliable tools and methods and thus is limited to research...

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Main Authors: Giovanni Marasco, Sinan Sadalla, Giulio Vara, Rita Golfieri, Davide Festi, Antonio Colecchia, Matteo Renzulli
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2021/6669480
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author Giovanni Marasco
Sinan Sadalla
Giulio Vara
Rita Golfieri
Davide Festi
Antonio Colecchia
Matteo Renzulli
author_facet Giovanni Marasco
Sinan Sadalla
Giulio Vara
Rita Golfieri
Davide Festi
Antonio Colecchia
Matteo Renzulli
author_sort Giovanni Marasco
collection DOAJ
description Sarcopenia is gaining attention as a negative prognostic factor in different fields of medicine, including chronic liver failure. However, the assessment of sarcopenia in patients with liver diseases is often neglected due to unawareness of reliable tools and methods and thus is limited to research studies. Cross-sectional imaging is a diffuse diagnostic tool and is commonly performed in patients with chronic liver failure. The last advancements in radiology image analysis using dedicated software allow an easy and standardized method to assess skeletal muscle volume. Several measures can be obtained from cross-sectional imaging analysis to evaluate sarcopenia in patients affected by chronic liver disease. We aimed to review the recent advances in imaging-based sarcopenia assessment, in particular in patients with chronic liver diseases. As a result, we found that the skeletal muscle index (SMI) seems to be a reliable method to assess sarcopenia in cirrhotic patients. Even if further studies are needed to validate proper cut-offs for each clinical endpoint, physicians are invited to consider the assessment of sarcopenia in the work-up of patients with chronic liver disease.
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publishDate 2021-01-01
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series Canadian Journal of Gastroenterology and Hepatology
spelling doaj-art-ce79614ad1ac44ae95fe9984c0fbb6cc2025-02-03T01:10:08ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972021-01-01202110.1155/2021/66694806669480Imaging Software-Based Sarcopenia Assessment in Gastroenterology: Evolution and Clinical MeaningGiovanni Marasco0Sinan Sadalla1Giulio Vara2Rita Golfieri3Davide Festi4Antonio Colecchia5Matteo Renzulli6Division of Gastroenterology, IRCCS, Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyDivision of Gastroenterology, IRCCS, Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyDivision of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyDivision of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyDepartment of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, Bologna 40138, ItalyUnit of Gastroenterology, Borgo Trento University Hospital of Verona, Verona, ItalyDivision of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalySarcopenia is gaining attention as a negative prognostic factor in different fields of medicine, including chronic liver failure. However, the assessment of sarcopenia in patients with liver diseases is often neglected due to unawareness of reliable tools and methods and thus is limited to research studies. Cross-sectional imaging is a diffuse diagnostic tool and is commonly performed in patients with chronic liver failure. The last advancements in radiology image analysis using dedicated software allow an easy and standardized method to assess skeletal muscle volume. Several measures can be obtained from cross-sectional imaging analysis to evaluate sarcopenia in patients affected by chronic liver disease. We aimed to review the recent advances in imaging-based sarcopenia assessment, in particular in patients with chronic liver diseases. As a result, we found that the skeletal muscle index (SMI) seems to be a reliable method to assess sarcopenia in cirrhotic patients. Even if further studies are needed to validate proper cut-offs for each clinical endpoint, physicians are invited to consider the assessment of sarcopenia in the work-up of patients with chronic liver disease.http://dx.doi.org/10.1155/2021/6669480
spellingShingle Giovanni Marasco
Sinan Sadalla
Giulio Vara
Rita Golfieri
Davide Festi
Antonio Colecchia
Matteo Renzulli
Imaging Software-Based Sarcopenia Assessment in Gastroenterology: Evolution and Clinical Meaning
Canadian Journal of Gastroenterology and Hepatology
title Imaging Software-Based Sarcopenia Assessment in Gastroenterology: Evolution and Clinical Meaning
title_full Imaging Software-Based Sarcopenia Assessment in Gastroenterology: Evolution and Clinical Meaning
title_fullStr Imaging Software-Based Sarcopenia Assessment in Gastroenterology: Evolution and Clinical Meaning
title_full_unstemmed Imaging Software-Based Sarcopenia Assessment in Gastroenterology: Evolution and Clinical Meaning
title_short Imaging Software-Based Sarcopenia Assessment in Gastroenterology: Evolution and Clinical Meaning
title_sort imaging software based sarcopenia assessment in gastroenterology evolution and clinical meaning
url http://dx.doi.org/10.1155/2021/6669480
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